What does a borderline risk result mean for Down syndrome screening?

Prenatal screening for Down syndrome is commonly known as Down screening. It is mainly based on extracting blood from pregnant women for testing, and then combining some conditions of the pregnant women to determine the probability of the fetus having Down syndrome. If the Down screening test report shows that the fetus is more likely to have Down syndrome, further diagnostic tests should be carried out. So what does the critical risk of Down syndrome screening mean?

What does Down syndrome screening critical risk mean?

Down screening is the general name for prenatal selection tests for Down syndrome. The purpose is to test the blood of pregnant women, test the concentrations of alpha-fetoprotein, human gonadotropin and free estriol in the blood cells of pregnant women, and combine the age, weight, and weeks of pregnancy of the pregnant women to determine the risk of congenital idiocy and neural tube defects in the fetus. The critical risk of Down syndrome screening belongs to the critical point risk, which means that there is a certain probability of getting sick. It is recommended that you go to the hospital outpatient department to do amniocentesis, which is more accurate than Down syndrome screening, but has certain risks. Mother can think about it herself.

Why do Down syndrome screening?

Check the actual significance

Down syndrome screening is used for special groups who do not have any corresponding symptom signs (such as all pregnant women). Through the test, key subjects who are most likely to suffer from Down syndrome can be selected for subsequent diagnosis-related examinations. Down syndrome has not been eradicated medically so far, so the key approach to controlling the occurrence of Down syndrome is to prevent or reduce the birth of patients. But one thing that needs to be established is that the purpose of screening is not to diagnose a certain disease, but to select people who are very likely to have a certain disease.

necessity

All pregnant women have the potential to conceive a baby with Down syndrome. "According to the birth defect detection data based on hospital outpatient clinics of the Ministry of Health from 2001 to 2006, 800,000 to 1.2 million babies with birth defects are born in my country every year." Down syndrome screening is a survey work currently carried out on all pregnant women in my country to prevent the birth of children with congenital mental retardation.

From a medical perspective, Down syndrome screening is very necessary and pregnant mothers must pay enough attention to it. Down syndrome screening can reduce the birth rate of Down syndrome children. Down syndrome children will have serious multiple developmental malformations (unusual appearance, congenital heart disease, abnormal function of major internal organs and physical abnormalities), accompanied by severe intellectual disabilities, and are basically unable to be independent in daily life. Most patients die before the age of 18. Therefore, in order to prevent the birth of children with congenital idiocy and ensure early detection and early treatment, prenatal Down syndrome screening is very important. Data show that "through strict quality control of early pregnancy NT screening, the diagnosis rate of 21-trisomy fetuses can exceed 80%, and the diagnosis rate of other chromosomal abnormalities can exceed 70%. If combined with maternal blood cell testing, the diagnosis rate can be further improved."