At what size does the follicle need to be to be released, and what is the reason for it not being released?

Poor or immature follicles will affect their size, and follicles that are too small cannot ovulate normally. Small and numerous follicles are due to insufficient hormone secretion and poor function of the body. Generally, follicles have three stages: primordial, growing and mature follicles. The size of follicles from primordial to growing and then to mature follicles is 18-25 mm. Most follicles below this size are immature. The size of the follicles also affects women's conception, so the follicles play a vital role.

Follicular dysplasia refers to the failure of follicles to reach the size of mature follicles in the late follicular stage, poor function, insufficient estrogen secretion, and clinical examination cervical scores that cannot reach the expected high value (>10 points). Our monitoring team found that this situation is very common in infertile women, with an incidence rate of up to 27.0%. Moreover, it occurs repeatedly in different cycles of the same patient, with a recurrence rate of up to 63.8%. Even in their non-FM cycles, there are often abnormalities of varying degrees. This finding suggests that FM may be an important cause of infertility.

Women of normal childbearing age ovulate once a month, usually about two weeks before the next menstrual period. The main organs that control ovulation are the hypothalamus, pituitary gland, and ovarian axis. The reasons why women do not ovulate include pituitary, hypothalamic, central nervous system, brain lesions, immune or mental factors. As long as women who do not ovulate receive reasonable treatment, the chances of normal ovulation and pregnancy are very high. However, the cause of the disease must be identified first, and then a diagnosis and treatment plan is developed based on the patient's specific situation. Further examination and treatment are recommended.

From our clinical experience, there are two effective treatment methods for it, one is medication, the other is surgery, neither of which can solve the fundamental problem from the cause. It can only relieve symptoms. The medication is hormonal drugs, such as Diane and estrogen and progesterone, and even ovulation-inducing drugs. The medication is effective, but it will relapse after stopping the medication. For those who are ineffective with fertility requirements, laparoscopic ovarian drilling is the most effective treatment method, and the pregnancy rate after surgery is over 90%. However, polycystic ovary is often accompanied by uterine septum or endometrial polyps. Digital dynamic hysterosalpingography or hysteroscopy is required for diagnosis. If there is a hysteroscopic septum and polypectomy, otherwise it is easy to cause habitual abortion.

It should be noted here that a few people will have relapses after surgery, but relapse does not mean that the surgery was done in vain, because the ovulation induction effect is very good at this time, and the medication is very effective, but it is not the case without surgery. For early treatment, the pregnancy rate after surgery can reach more than 90%, and menstruation will gradually return to normal. In addition, it can prevent the long-term and continuous stimulation of estrogen on the endometrium, and delayed menopause can easily lead to endometrial cancer. It can also prevent changes in body shape. Often some patients will become fatter and fatter because of this disease, and no matter what medicine they take, they cannot change their body shape, so they should be treated in time.