Why is the endometrium thick?

Thick endometrium is a common gynecological disease, which causes great harm to women's health. There are many reasons that lead to thick endometrium, such as unbalanced hormone secretion, female anovulation, ovarian dysfunction, obesity, etc. In addition, endocrine functional tumors and endometrial hyperplasia can easily lead to thick endometrium.

- Anovulation: Some women do not ovulate, which causes the endometrium to be continuously affected by estrogen for a long time without progesterone to counteract it. As a result, the endometrium lacks the transformation of the cyclical secretory phase and is in a state of hyperplasia for a long time.

2. Obesity: Obese people are at high risk of endometrial thickening because androstenedione secreted by the adrenal glands of these women is converted into estrone through the action of aromatase in adipose tissue. The more adipose tissue there is, the stronger the conversion ability is, and the higher the estrone level in the plasma is, thus causing a persistent estrogen effect.

3. Endocrine functional tumors: Endocrine functional tumors are still rare in clinical practice, accounting for 7.5%. The gonadotropin function of the pituitary gland is abnormal, and ovarian granulosa cell tumor is also a tumor that continuously secretes estrogen.

4. Endometrial hyperplasia: Endometrial hyperplasia is different from endometriosis. It is a pathological thickening of the endometrium. The diseased uterus will be slightly larger, the endometrium will be significantly thickened, and it will appear diffusely polyp-like.

The above is a detailed introduction to the causes of endometrial thickening. I believe patients should know which factors can cause the disease. Since this disease is very harmful to patients, we hope that female friends can pay more attention to it. If you find that you have this disease, you should go to the hospital for treatment as soon as possible.