What causes thick endometrium?

There are many reasons for the thick endometrium. Some women will have heavy menstrual flow. When you go to the hospital for examination, the doctor will often tell you that the endometrium is thick. This is also a common gynecological disease, which will have a great adverse effect on your health. Poor hormone secretion, ovarian dysfunction, endocrine and other reasons will lead to the gradual thickening of the endometrium. In addition, obesity is also a cause of endometrial thickening.

Generally speaking, endometrial thickening is caused by the following reasons:

1. Distribution of hormone receptors

Complex endometrial thickening is related to the distribution of hormone receptors. This type of endometrial thickening may be polyp-like, and complex endometrial thickening may be mixed with other types of thickening such as uterine atrophy.

2. Ovarian dysfunction

If the ovarian hormones are disordered, it can easily lead to abnormal endometrial thickening, which is called endometrial hyperplasia. The clinical manifestations are irregular and excessive abnormal uterine bleeding. Patients may experience continuous bleeding after a long period of amenorrhea. Some patients also experience shortened cycles and prolonged menstruation, and the bleeding time can be up to 1 month.

3. Abnormal estrogen secretion

The hormone glands in women's bodies secrete hormones unbalancedly, resulting in anovulation. The endometrium is affected by estrogen for a long time, and there is no transformation from a cyclical secretory phase. The endometrium is in a thickened state for a long time. This is a common cause of thickening of the uterine lining in women.

4. Endocrine Functional Tumors

Functional endocrine tumors lead to abnormal gonadotropin function of the pituitary gland and the occurrence of ovarian granulosa cell tumors, which can also cause thickening of the endometrium in women.

5. Obesity

The adrenal glands of obese women secrete androstenedione, which is converted into estrone after the action of aromatase in the adipose tissue. The estrone level in the plasma rises, which makes it easy for persistent estrogen effects to occur, causing thickening of the female endometrium.