What is the cause of vulvar leukoplakia?

Women must pay special attention to their reproductive health issues, and any abnormal conditions in the reproductive parts should be taken seriously. The causes of vulvar leukoplakia include genital infection, some inflammatory stimulation or endocrine disorders, as well as vitiligo, vulvar eczema and other diseases, which may lead to the formation of leukoplakia.

1. Vulvar infection and inflammatory stimulation: This is the main cause of vulvar leukoplakia, accounting for about 50% of patients. There are many factors that cause vulvar infection and inflammatory irritation, such as poor hygiene habits, not often using pH 4 weak acid formula feminine care solution to clean the vulva, wearing synthetic underwear, unclean sanitary products, bathing in a bathhouse, swimming in a bathhouse, etc., which lead to vaginal inflammation. If it is not treated in time, the inflammatory secretions will infiltrate the perineum, and long-term infection and irritation will damage the skin and mucous membranes, causing redness, swelling, ulcers and degeneration, which will gradually develop into vulvar leukoplakia.

2. Endocrine disorders: Endocrine diseases are caused by pathological changes in the endocrine glands and tissues themselves, or by endocrine disorders due to genetics, enzyme defects, immune function and other reasons. Through the determination of tritium (H3) labeled thymidine, it is believed that there is a protein hormone in the dermis that can inhibit the division and growth of epidermal cells and only acts locally on the epidermis with tissue specificity, called inhibin. It causes an imbalance between local connective tissue hyperplasia and the stimulation of epidermal metabolism at that location, leading to vulvar leukoplakia.

3. Genetic factors: About 10-30% of patients with vulvar leukoplakia. It is caused by genetics. The genetically caused vulvar leukoplakia is mainly atrophic type, and the patients are mainly young girls. In clinical practice, the first thing to pay attention to for patients under 15 years old is genetic factors, and inquire whether there are patients with vulvar leukoplakia in their parents' family.

4. Other diseases: such as diabetes, vitiligo, vulvar eczema, vulvar itching, etc., if the drugs are abused or the treatment is improper, it may also cause or aggravate the formation and development of vitiligo.

There are many causes of vulvar leukoplakia, but the main cause is vaginal infection and inflammatory stimulation. Therefore, female friends must pay more attention in their daily lives to reduce the occurrence of infection and vaginal inflammation. This requires starting from hygiene, diet and other aspects.