Can uterine fibroids be cured?

When it comes to uterine fibroids, many women are worried because the incidence of this reproductive disease is getting higher and higher. If it is not controlled and treated, the harm will be greater. Uterine fibroids can be treated. There are some common drugs, but they must be treated according to the symptoms.

(1) Gonadotropin- releasing hormone agonist (GnRH-a). The GnRH-a commonly used in clinical practice include leuprorelin (Enanton), goserelin (Zoloft), triptorelin (Dapiga), etc. GnRH-a should not be used continuously for a long time. It is only used for pretreatment before surgery, generally for 3 to 6 months, to avoid causing severe menopausal symptoms caused by low estrogen. A small dose of estrogen can also be supplemented at the same time to counteract this side effect.

(2) Mifepristone: It is a progesterone antagonist. In recent years, it has been clinically tried to treat uterine fibroids. It can reduce the size of fibroids, but the fibroids often grow again after stopping the drug.

(3) Danazol: used for preoperative medication or treatment of uterine fibroids that are not suitable for surgery. Uterine fibroids may grow larger after medication is stopped. Danazol can cause liver damage and androgenic side effects (weight gain, acne, dull voice, etc.).

(4) Tamoxifen: can inhibit the growth of fibroids. However, long-term use may cause enlargement of uterine fibroids in some patients, and may even induce endometriosis and endometrial cancer, so this should be paid attention to.

(5) Androgen drugs: Commonly used drugs include methyltestosterone (methyltestosterone) and testosterone propionate (testosterone propionate), which can inhibit the growth of fibroids. The dosage should be used carefully to avoid virilization.

During the bleeding period of patients with uterine fibroids, if the amount of bleeding is heavy, uterine contractants (such as oxytocin, ergot) and hemostatic drugs (such as hemostatic acid, aminobenzoic acid (hemostatic aromatic acid), lizhihemostasis, Panax notoginseng tablets, etc.) can also be used, which can play a certain degree of auxiliary hemostatic effect.