Which blood type is more prone to hemolysis than type O blood? Introducing the authoritative answer

Which blood type is more prone to hemolysis than type O blood? Introducing the authoritative answer

If both the man and the woman have type O blood, the child born will not be likely to have ABO hemolytic disease. However, if the woman has type O blood and the man does not have type O blood, the probability of the baby having ABO hemolytic disease will greatly increase. Therefore, this is determined by the blood types of both parents.

1. If a woman with type O blood and a man with what blood type have children who are more likely to have hemolytic disease,

Considering that babies born to men with type A, B or AB fertility types have an increased chance of developing ABO hemolytic disease.

Suggestions: Therefore, in such a situation, it is best to do a blood type antibody test for the mother and an amniotic fluid test.

2. If the mother's blood type is O and the father's blood type is A, B or AB, ABO incompatibility hemolytic disease is likely to occur. Not all babies born to O-type mothers will develop hemolytic disease. Some babies will get the disease, some will not. Some symptoms are mild, and some are severe. This is related to the amount of maternal antibodies, the degree of binding of antibodies to fetal red blood cells, the strength of A or B antigens and the fetal compensatory hematopoietic ability. "ABO hemolytic disease" often occurs in the second pregnancy, but it may also occur partially in the first pregnancy. If the mother has a history of miscarriage (the mother's birth canal is damaged and the blood of the aborted fetus enters the body), the mother will produce anti-A or anti-B antibodies. Then even the first baby may develop neonatal hemolytic disease.

3. If a woman has type O blood and the man has an inconsistent blood type, it can easily lead to a hemolytic reaction, but it will not directly cause cerebral palsy. Among all ABO blood-incompatible couples, true hemolysis is very rare. It is recommended to closely observe whether there is hemolysis after pregnancy.

4. Since there are neither A antigen nor B antigen on the red blood cells of type O blood, after being transfused into A, B, or AB type people, the O type red blood cells will not be bound by the relative anti-A or anti-B antibodies in the recipient's serum. Therefore, the transfused O type red blood cells will not be destroyed, but will perform their good function of carrying oxygen and eliminating carbon dioxide. People call people with type O blood "universal blood donors" only for this reason. Under normal circumstances, it is not recommended to transfuse O-type blood to people with other blood types because the serum of O-type blood contains anti-A and anti-B antibodies. After being transfused into the body of a person with other blood types, it can agglutinate with the red blood cells in the recipient's blood and then produce hemolysis. Because the amount of blood transfused is small and the amount of blood in the recipient's body is large, the chance of hemolysis of the bound red blood cells can be reduced through dilution in the blood circulation and the neutralization of some anti-A and anti-B antibodies in the O-type serum by some type A or type B blood type substances in the recipient's plasma. However, if the amount of O-type blood transfused is large and the concentration of anti-A and anti-B antibodies in the serum is very high, serious transfusion reactions may also occur. This shows that the "universal blood transfusion" is not omnipotent and it also poses serious risks. Based on the above introduction, it is believed that, except in special circumstances, O-type blood cannot be donated to people with other blood types. Adherence to the same type of blood transfusion should be regarded as the most important basic principle in the field of blood transfusion.

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