The endometrium can be affected by abortion, childbirth, environment, etc., and different types of endometrial diseases can occur. The most common ones are inflammation of the endometrium and endometrial thickening. Endometrial thickening is also endometrial hyperplasia, which belongs to the same disease range. When the patient develops the disease, the cause of the disease must be found so that targeted treatment can be given. So how should endometrial thickening be treated? In order to treat the disease, the patient must diagnose the severity of the disease and take symptomatic treatment. Endometrial hyperplasia has a certain tendency to become cancerous, so it is classified as a precancerous lesion. However, based on long-term observations, the vast majority of endometrial hyperplasia is a reversible lesion or maintains a persistent benign state. Only in a few cases may cancer develop after a longer time interval. It is divided into three types according to the changes in glandular structure and morphology and the presence or absence of glandular epithelial cell atypia: ① Simple hyperplasia: a physiological response of the endometrium caused by long-term stimulation of estrogen without progesterone antagonism. The stroma and glands proliferate simultaneously without glandular crowding, and the morphology of the glandular epithelium is not atypical. ② Complex hyperplasia: The glands in the lesion area are crowded, the stroma is significantly reduced, and there is no atypia of the glandular epithelial cells. ③ Atypical hyperplasia: The glandular epithelium is atypical and belongs to the intraepithelial neoplasm of the endometrium. According to the severity of the lesion, it is divided into three degrees: mild, moderate and severe. 1. The principle of drug treatment is Standardized medication, long-term examinations, regular testing, and timely assisted pregnancy. Types of medication: ① The ovulation-inducing drug clomiphene is taken once a day on the 5th to 9th day of the cycle. If necessary, the medication period can be extended by 2 to 3 days. ② Progestin drugs: They vary according to the degree of endometrial atypicality. Mild atypical hyperplasia can be treated with intramuscular injection of progesterone, starting on the 18th or 20th day of the cycle, and taken for 5-7 days. Patients with moderate and severe atypical hyperplasia should use medroxyprogesterone continuously for a course of 3 months. After each course of treatment, a curettage or removal of endometrial tissue should be performed for histological examination. Depending on the response to the drug, the patient can choose to stop treatment or increase or decrease the dosage of the drug as appropriate. An intrauterine ring can also be placed. 2. Surgery Curettage and aspiration is not only an important diagnostic method, but also one of the treatment methods. Because local lesions can also be removed through curettage. Patients with atypical endometrial hyperplasia who are over 40 years old and have no fertility requirements can undergo hysterectomy once diagnosed. However, for patients with hypertension, diabetes, obesity or advanced age who have poor tolerance to surgery, drug treatment may be considered under close follow-up monitoring. Young patients who have not responded to drug treatment, whose endometrial hyperplasia continues or worsens or is suspected of having developed cancer, whose vaginal bleeding cannot be controlled by curettage and drug treatment, and whose condition recurs after delivery, may all consider surgical removal of the hysterectomy. How to treat thick endometrium? When treating diseases caused by thick endometrium, patients need to adjust their mood first, then make a formal examination and diagnosis. After the disease is confirmed, they should follow the doctor's instructions for treatment. Treatment must have certain principles, not random treatment. During the treatment, patients should have regular check-ups and observe the improvement of the symptoms of the disease. The medication also needs to be changed regularly. Treating the disease according to the symptoms of the body will control the recovery of the disease. |
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