Treatment of hyperprolactinemia

Many people suffer from hyperprolactinemia, which causes serious harm to their bodies. Therefore, many patients with this disease want to choose treatment as soon as possible to prevent the disease from continuing to harm their bodies and recover as soon as possible. So what are the treatments for hyperprolactinemia? Let's take a look at the following introduction.

1. Anti-prolactin drugs

Antiprolactin includes bromocriptine, long-acting bromocriptine, tergoline, cabergoline, terguride, methylergoline, quinagoline, and lisuride.

2. Surgery

It is suitable for patients with giant adenoma and intracranial compression symptoms, who are unresponsive to bromocriptine treatment, giant adenoma, and serotonin-positive cell tumors and secrete multiple pituitary hormones. The current transsphenoidal microsurgery is safe, convenient, and easy to perform, and its efficacy is similar to that of bromocriptine therapy. Using bromocriptine before and after surgery can improve the efficacy. The disadvantages of surgery are that pituitary tumors have no obvious capsule and unclear boundaries, making it difficult to perform a thorough surgery or causing damage, leading to cerebrospinal fluid nasal fistula and postoperative hypopituitarism. It is worth noting that although preoperative treatment with bromocriptine can shrink the tumor, it can cause tumor fibrosis, sclerosis and adhesion of surrounding tissues, which is not conducive to surgical separation and resection. Therefore, if surgery is determined, preoperative medication can be temporarily stopped, and medication or radiotherapy can be supplemented after surgery.

The mortality rate of microsurgical resection of pituitary prolactin adenomas is less than 0.5%, the incidence of temporary postoperative diabetes is 10% to 40%, and the incidence of permanent diabetes and iatrogenic hypothyroidism is less than 2%. The probability of prolactin and ovulation returning to normal after surgery for microadenomas is 65% to 85%, while for macroadenomas it is 20% to 40%, and 85% of patients have normal visual fields.

3. Chemotherapy

It is suitable for non-functional tumors of the hypothalamus-pituitary system and for those who have not responded to drug and surgical treatments. Currently, advanced stereo focused radiotherapy methods are mostly used, including: deep X-rays, γ, 60Co, α particles and proton rays, radionuclide 90Y, 198Au pituitary implants, etc.

The above content specifically introduces the treatment methods of hyperprolactinemia. Therefore, for patients with this disease, do not ignore the harm of this disease. You must actively carry out effective treatment to recover. The above is a detailed introduction. You can use the treatment methods introduced above to get effective treatment and recover as soon as possible.