Causes of high total bile acid in pregnant women

New mothers who are pregnant will encounter a problem: high bile acid levels in pregnant women. This is a problem of particular concern during pregnancy. Many people do not understand the harm this disease can cause and think that taking some medicine will solve the problem. In fact, this is not the case. Let us learn about the treatment of this disease and the causes of this disease.

Bile acid is another sensitive indicator reflecting acute hepatocellular damage.

The high total bile acid level in pregnant women is due to abnormal bile acid metabolism and changes in hormone levels during pregnancy. Pregnant women with high total bile acid levels are prone to intrahepatic cholestasis.

Due to the increase of estrogen and progesterone in pregnant women during pregnancy, the smooth peristalsis of the bile duct is inhibited, resulting in poor drainage of bile acid and bile stasis in the liver. The bilirubin and bile acid in the bile reflux into the blood through the hepatic sinusoids and are carried to the whole body of the pregnant woman and fetus through the blood circulation. Excessive bilirubin can pass through the fetal blood-brain barrier to form "kernicterus" and affect intellectual development.

Excessive bile salts stimulate the skin nerves of pregnant women and cause itching. Its main hazards are increasing premature birth, fetal distress and fetal mortality, and increasing the incidence of postpartum hemorrhage in pregnant women.

The above introduces to friends the reasons why total bile acid in pregnant women is high. You can see that the causes of this disease will lead to quite serious consequences and cannot be ignored. This disease has a great impact on the fetus, so friends should pay attention to it.