How long can a woman live with pyelonephritis?

Pyelonephritis can be divided into two types: chronic pyelonephritis and acute pyelonephritis. After the disease occurs, there will be symptoms such as fever, frequent urination, urgency, pain when urinating, and bacteriuria, which have a great impact on the patient's normal life. Pyelonephritis is a kidney disease, and many female patients worry that they will not live long after becoming ill. So, how long can women live with pyelonephritis? Let’s take a look below.

If the complications are few and well controlled, they generally will not affect life. However, if left untreated and combined with other complications, the disease will progress, resulting in varying degrees of renal impairment and eventually developing into chronic renal failure. The average lifespan is about 20 to 30 years, and can reach 50 years.

treat

The purpose is to relieve symptoms, control infection, clear infected lesions, correct urinary tract abnormalities or reflux, prevent complications, prevent recurrence, and reduce damage to the renal parenchyma.

1. General treatment

Patients are encouraged to drink more water, urinate frequently, and not hold urine to reduce medullary osmotic pressure, improve the body's phagocyte function, and flush out bacteria in the bladder. If you have symptoms of systemic infection such as fever, you should rest in bed. When there are symptoms of bladder irritation, sodium bicarbonate can be given to alkalinize the urine and relieve the symptoms. For those with vesicoureteral reflux, the "double urination method" can be used, that is, urinating again 5 minutes after urinating.

2. Acute pyelonephritis

(1) Mild cases are treated mainly with oral antibiotics for 14 days. Before taking the medicine, collect urine for bacterial culture and drug sensitivity test. First, choose drugs that are effective against Gram-negative bacteria, such as quinolones, semi-synthetic penicillins and cephalosporins. After 72 hours of treatment, whether to continue the treatment should be evaluated based on the efficacy. If symptoms have not improved, effective antibiotics should be selected based on drug sensitivity tests. Recheck urine after 14 days of treatment. If bacteriuria is still positive, sensitive antibiotics should be used to continue treatment for 6 weeks.

(2) Patients with severe systemic poisoning symptoms should be given sensitive antibiotics intravenously and combined with other medications if necessary. After the body temperature returns to normal, clinical symptoms improve, and urine bacterial culture turns negative, oral medications should be used to complete a course of treatment of no less than 2 weeks. Attention should be paid to whether complications such as pyonephrosis and perinephric abscess occur.

(3) Infant and young children Acute pyelonephritis in newborns, infants and children under 5 years old is often accompanied by urethral malformations and dysfunctions, so it is difficult to eradicate. However, some functional disorders such as vesicoureteral reflux may disappear with age. One-time or multiple urinary tract infections can form focal scars in renal tissue and even affect renal development. In recent years, it has been advocated to perform midstream urine bacterial culture before medication whenever possible, and urine culture should be repeated 2, 4, and 6 weeks after medication discontinuation in order to detect and treat the disease in a timely manner.

3. Chronic pyelonephritis

(1) Correction and removal of predisposing factors The key to the treatment of chronic pyelonephritis is to actively identify and remove predisposing factors, and to correct and remove existing urinary system anatomical abnormalities, stones, obstruction, and reflux as much as possible.

(2) Anti-infection treatment: The treatment for acute attacks is the same as that for acute pyelonephritis. After collecting urine specimens for bacterial culture, drugs effective against Gram-negative bacteria are immediately given. If the concentration of antibiotics in the lesion is insufficient due to bacterial resistance or scar formation at the lesion site, poor blood flow, or insufficient antibiotic concentration, a higher dose of bactericidal antibiotics may be tried for a course of 6 weeks. If the obstructive factors are difficult to eliminate, appropriate antibiotics should be selected based on drug sensitivity for treatment for 6 weeks. Long-term low-dose treatment may also be considered. Generally, low-toxic antibiotics are selected for treatment.

(3) Glucocorticoids and nonsteroidal anti-inflammatory drugs can reduce the occurrence and development of renal scarring caused by infection.

(4) Protecting renal function: Increased blood pressure can accelerate the deterioration of renal function, so attention should be paid to controlling blood pressure during the long-term treatment of chronic pyelonephritis. Improve microcirculation, improve blood supply to the kidneys, and prevent further damage to renal function. Patients with renal insufficiency should be treated according to the chronic renal insufficiency, given a low-protein diet, and prohibited from taking nephrotoxic drugs.