Is 25 normal for women?

The basic sedimentation rate of blood cells, commonly known as erythrocyte sedimentation rate, refers to the rate at which blood cells settle under a certain standard. Some women get an ESR of 25 when tested, which makes them unable to judge their condition. So, is an ESR of 25 normal for women?

Slightly higher, the normal standard value is: adult male 0-15mm/h adult female 0-20Mm/h. Your threshold is slightly higher, which should not be a big problem and may not be of great significance. It still needs to be comprehensively judged in combination with your other test indicators. This situation may also occur if a woman is menstruating or the elderly. If not, look for other possible causes.

Clinical manifestations of erythrocyte sedimentation rate

1. An increase in ESR is more common in clinical medicine. According to the Wei's method, for both men and women, an ESR value of 25 mm/h is considered slightly increased; 50 mm/h is considered slightly to moderately increased; and more than 50 mm/h is considered moderately to severely increased. According to the Pan method, whether men or women, if the ESR reaches 20 mm/h, it is considered to be fast.

(1) Physiological acceleration: The ESR rate of women increases slightly during menstruation, which may be related to the rupture of the uterine wall and bleeding. After three months of pregnancy, the ESR rate gradually increases, reaching 30 mm/h or a large amount, and it will gradually recover until three weeks after the pregnant woman gives birth if there are no complications. Its rapid change may be related to physiological anemia, gradual increase in fibrinogen level, placental detachment, birth injury, etc. Elderly people over 60 years old also generally have faster erythrocyte sedimentation rate due to the gradual increase in blood fibrinogen quality.

(2) Physiological changes: various inflammations of blood pressure: during bacterial inflammation, the acute phase reactants in the blood increase rapidly, including α-antirypsin, α2-mactoglobulin, C reactive protein, haptoglobin, transferrin, fibrinogen, etc., mainly due to increased release and even increased production. The above ingredients can more or less promote the ribbon-like aggregation of blood cells, so the erythrocyte sedimentation rate can be seen to increase 2-3 days after the inflammation occurs. The pathological changes of rheumatic fever include symptoms of connective tissue inflammation, and the erythrocyte sedimentation rate becomes faster during the active phase. In inflammation such as tuberculosis, the fibrinogen and human immunoglobulin components increase, and the erythrocyte sedimentation rate becomes significantly faster. In clinical medicine, the most common erythrocyte sedimentation rate is used to observe the activity and changing patterns of tuberculosis and rheumatic fever. Hyperglobuinemia caused by various reasons in the blood: In hyperglobuinemia caused by acute infective endocarditis, kala-azar, lupus erythematosus, etc., the ESR often becomes significantly faster. In cases of relative blood protein increase caused by other reasons, such as chronic nephritis and liver cirrhosis, the ESR also often becomes faster. In multiple myeloma and macroglobulinuria, the malignant transformation and proliferation of plasma cells causes the physiological globulin in the blood to reach 40-100g/L or higher, so the erythrocyte sedimentation rate becomes faster. In patients with macroglobulinemia, the IgM in the blood increases, and their erythrocyte sedimentation rate should become faster. However, if the IgM increases significantly and the blood viscosity increases, that is, hyper-stickiness syndrome, it will inhibit the erythrocyte sedimentation rate and obtain a normal or even alleviated result. In addition, malignant tumors, tissue damage and necrosis, anemia, and high cholesterol accumulation syndrome can all cause the ESR to increase.

2. The actual significance of slow erythrocyte sedimentation rate is relatively small. It can be caused by a significant increase in the number of blood cells and a serious decrease in the fibrinogen component, which is common in dehydrated blood extraction caused by various reasons, pathological erythrocytosis and focal intravascular coagulation.