How is warm nest syndrome treated?

Ovarian syndrome is still a relatively common gynecological disease. There are many causes of this disease. Everyone can pay more attention to treatment, especially to develop good living habits in normal times. At the same time, everyone should also pay attention to this disease, because this disease is relatively easy to treat. Now the editor will give you a detailed introduction.

1. Obesity and insulin resistance

Increase exercise to lose weight, correct endocrine and metabolic disorders aggravated by obesity, reduce insulin resistance and hyperinsulinemia, reduce IGF-1, increase IGfBP-1, and at the same time increase SHBG to reduce free androgen levels. Losing weight can restore ovulation in some obese women with PCOS and prevent the occurrence of type 2 diabetes and cardiovascular disease. Metformin treatment can be used for patients with or without diabetes. It can effectively reduce body weight, improve insulin sensitivity, lower insulin levels, reduce hair loss, and even restore menstruation (25%) and ovulation. Since obesity and insulin resistance are the main causes of PCOS, any drug that can reduce weight and increase insulin sensitivity can treat this syndrome.

2. Drug-induced ovulation

(1) Clomiphene is the drug of choice for PCOS, with an ovulation rate of 60% to 80% and a pregnancy rate of 30% to 50%. Clomiphene competes with endogenous estrogen receptors at the hypothalamus-pituitary level, inhibits estrogen negative feedback, increases the pulse frequency of GnRH secretion, and thus adjusts the secretion ratio of LH and FSH. Clomiphene also directly stimulates the ovaries to synthesize and secrete estrogen. After taking this drug, the ovaries may enlarge due to overstimulation (13.6%), vasodilation may cause hot flashes (10.4%), abdominal discomfort (5.5%), blurred vision (1.5%), or side effects such as rash and mild hair loss may occur.

During treatment, it is necessary to record the basal body temperature of the menstrual cycle, monitor ovulation, or measure serum progesterone and estradiol to confirm whether ovulation occurs and guide the adjustment of the dosage for the next treatment course. If there is still no ovulation or conception after 6 to 12 months of clomiphene treatment, clomiphene plus HCG or glucocorticoids, bromocriptine or HMG, FSH, GnRH, etc. can be given.

The above are several treatment methods introduced by the editor. Everyone should have seen them very clearly. The best treatment method is that female friends need to pay more attention to their daily lives. Because prevention is the best treatment, everyone should pay attention to it once they are diagnosed with the disease.