What tests should be done if follicle development is poor?

Poor follicular development is one of the main causes of female infertility, mainly due to the inability to discharge mature eggs. However, this symptom will not cause obvious physical abnormalities in patients and can only be diagnosed through corresponding examinations. So what kind of instruments do patients need to use for examination? What are the inspection items? Let me solve these problems for you in detail.

Generally speaking, starting from the 8th day of the menstrual cycle, ultrasound monitoring should be done once every 2 days. When the diameter of the follicle is found to be 17 mm, monitoring should be changed to once a day. When the follicle matures and reaches a diameter of 20-23 mm, it should be measured twice a day if necessary until ovulation.

1. Endocrine hormone examination: The levels of FSH and LH are significantly increased, and the level of E2 is significantly decreased, both reaching menopausal levels. Three tests are required to confirm the diagnosis.

2. Vaginal exfoliated cells: Indicates low estrogen levels, with the presence of bottom-layer cells or mainly bottom-layer cells.

3. Laparoscopic examination: In patients with premature ovarian failure, the ovaries are small and atrophic, the follicles are not obvious, no primordial follicles are seen under the microscope, the ovarian stroma is fibrotic, and anti-ovarian antibodies can be found in the ovaries. In patients with unresponsive ovary syndrome, the ovaries are normal in size, and multiple small follicles can be seen both with the naked eye and under the microscope. Anti-theca cell, anti-granulosa cell, and anti-FSH antibodies can be found in the ovarian tissue.

4. Ultrasound manifestations of follicular development: small ovaries with no follicles indicate premature ovarian failure, while normal-sized ovaries with multiple small follicles indicate unresponsive ovary syndrome. Time of follicle appearance: At the beginning of each menstrual cycle, multiple follicles develop simultaneously, but generally only one or two follicles develop to maturity, which are called primary follicles. Follicle growth rate: Ultrasound can detect small follicles in the ovaries on the 3rd to 5th day of the menstrual cycle.

The examination items introduced in the article are all necessary. If a woman suspects that her follicles are not developing well, it is best to go to the gynecology clinic for examination to accurately determine her condition. At the same time, it is important to take appropriate measures for treatment in a timely manner. Patients generally have to wait until the follicles return to normal before starting to get pregnant.