[Medical Q&A] What is premature ovarian failure?

Author: Li He, deputy chief physician, Shanghai Ji'ai Genetics and Infertility Diagnosis and Treatment Center, Obstetrics and Gynecology Hospital, Fudan University

Reviewer: Fu Jing, Chief Physician, Shanghai Ji'ai Genetics and Infertility Diagnosis and Treatment Center, Obstetrics and Gynecology Hospital, Fudan University

Premature ovarian failure or primary ovarian insufficiency refers to the decline or cessation of ovarian function before the age of 40.

The time that the ovaries can exert their reproductive endocrine function is figuratively referred to as ovarian age. Just like the characteristics of physiological age, aging ovaries will also show abnormal endocrine indicators, decreased ovarian function and reduced fertility.

Generally speaking, a woman's physiological age represents her ovarian age. The ovarian function of women aged 20 to 30 is relatively strong, while women over 40 will experience a decline in ovarian function. However, some women's ovarian age is seriously inconsistent with their physiological age, which is manifested as a decline in ovarian function when they are younger. If ovarian function declines or stops before the age of 40, it is clinically called premature ovarian failure or primary ovarian insufficiency.

Therefore, we recommend that you try to have children as early as possible at the right age and not miss the best opportunity to have children. If you find any signs of premature ovarian failure, it is recommended that you seek help from a professional doctor immediately.