[Medical Q&A] Why does hydrosalpinx lead to infertility?

Author: Li He, deputy chief physician, Shanghai Ji'ai Genetics and Infertility Diagnosis and Treatment Center, Obstetrics and Gynecology Hospital, Fudan University

Reviewer: Fu Jing, Chief Physician, Shanghai Ji'ai Genetics and Infertility Diagnosis and Treatment Center, Obstetrics and Gynecology Hospital, Fudan University

The effects of hydrosalpinx on pregnancy mainly include the following aspects:

(1) Hydrosalpinx will directly affect the reproductive physiological functions of the fallopian tube, including the intake of eggs, the transportation of eggs and embryos, and the transportation and activation of sperm.

(2) Hydrosalpinx can affect the receptivity of the endometrium. The retained fluid flowing into the uterine cavity can cause hydrosalpinx, which can mechanically interfere with the contact between the embryo and the endometrium.

(3) The microorganisms and toxic substances contained in the stagnant water can also affect embryo implantation.

(4) Hydrosalpinx is toxic to the embryo and can cause abnormal and obstructed embryo development.

The fallopian tube is the reproductive logistics channel for transporting sperm, eggs and embryos. Changes in the fallopian tube caused by inflammation are like a blockage in the "logistics channel", and hydrosalpinx is a serious event caused by the blockage of the logistics channel and simmering inflammation.