1. Diabetic nephropathy 1. Characteristics: Long-term high blood sugar leads to renal microvascular disease, and the disease progresses gradually. The early symptoms may not be obvious, but as the disease progresses, symptoms such as proteinuria and edema will appear. 2. Risk factors: Poor blood sugar control is the key to worsening the disease. If the patient cannot strictly control blood sugar, kidney damage will continue to worsen and the risk of uremia will increase significantly. 3. Notes: Diabetic patients need to regularly check urine protein, kidney function and other indicators, and strictly follow the diabetes treatment plan, including diet control, exercise, drug therapy, etc., to delay the progression of kidney disease. 2. Hypertensive nephropathy 1. Manifestations: Long-term hypertension increases the pressure in the glomerulus, causing renal arteriosclerosis and impaired renal function. The main manifestations in the early stage are increased nocturia, and gradually proteinuria and hematuria. 2. Risk factors: Large fluctuations in blood pressure and failure to effectively control it. If the patient does not take antihypertensive drugs on time, blood pressure will remain at a high level for a long time, which will accelerate kidney disease and increase the probability of uremia. 3. Prevention points: Hypertensive patients should monitor their blood pressure regularly, take antihypertensive drugs regularly, and keep their blood pressure stable. At the same time, pay attention to a low-salt diet to reduce the burden on the kidneys. 3. Polycystic Kidney 1. Characteristics: The kidneys are covered with cysts of varying sizes. The cysts continue to grow, compressing normal kidney tissue, causing a gradual decline in kidney function. Patients may experience symptoms such as low back pain, abdominal mass, and hematuria. 2. Factors that contribute to the progression of the disease: Rapid cyst growth and repeated complications such as infection and bleeding. These conditions will accelerate the damage to kidney function and increase the risk of uremia. 3. Countermeasures: Perform regular renal ultrasound examinations to monitor cyst size and changes in renal function. Avoid strenuous exercise and external impact on the abdomen to prevent cyst rupture. Actively treat complications and consider surgical intervention if necessary. 4. IgA Nephropathy 1. Symptoms: The main feature is the deposition of IgA in the glomerular mesangial area. The clinical manifestations are diverse and may include asymptomatic hematuria, proteinuria, and may also be accompanied by hypertension, renal dysfunction, etc. 2. Poor prognostic factors: persistent large amounts of proteinuria, poorly controlled hypertension, severe pathological types (such as high degree of glomerular sclerosis and interstitial fibrosis), etc. These factors will gradually worsen the condition and increase the possibility of developing uremia. 3. Treatment points: Actively control blood pressure, reduce proteinuria, and select appropriate immunosuppressants and other drug treatments according to the pathological conditions. Regularly review urine routine, renal function and other indicators, and adjust the treatment plan in a timely manner. 5. Lupus nephritis 1. Characteristics: Systemic lupus erythematosus affects the kidneys, and the condition is complex and changeable. Symptoms such as proteinuria, hematuria, edema, and hypertension may occur, and may also be accompanied by multi-system damage. 2. Risk factors: high disease activity, irregular or untimely treatment. If lupus activity is not effectively controlled, kidney inflammation persists, kidney function will rapidly deteriorate, leading to uremia. 3. Management methods: Patients need to use glucocorticoids, immunosuppressants and other drugs in a standardized manner under the guidance of rheumatologists to control lupus. At the same time, they should regularly review relevant indicators, pay attention to rest, and avoid infection, sun exposure and other inducing factors. For patients with these kidney diseases, they should pay close attention to changes in their condition, actively cooperate with doctors' treatment, and take effective management measures to reduce the risk of uremia and improve their quality of life. |
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