Are you affected by these early signs of uremia?

40-year-old Mr. Li went to the gastroenterology department of the hospital because of loss of appetite and nausea. Examination revealed that he had uremia. Mr. Li couldn't understand how a simple nausea could lead to uremia?

In fact, the human body produces a lot of metabolic wastes during metabolism, which are harmful to the body. Under normal circumstances, the body will excrete these "wastes" through certain excretion pathways, including the gastrointestinal tract, respiratory tract, kidneys and skin, so as to ensure the normal physiological activities of the human body. If toxins cannot be excreted through the kidneys in a timely and effective manner and accumulate in the body, they will cause diseases of the digestive system, cardiovascular system, blood system, and even neuropsychiatric system. Lao Li has developed renal failure due to long-term kidney disease and has not received timely and effective treatment. The residual function of the kidneys is not enough to process and excrete these metabolic toxins. The accumulated toxins in the body stimulate the gastrointestinal tract, causing loss of appetite and nausea. In addition, uremia can lead to an imbalance of electrolytes (such as potassium, sodium and phosphorus), which can affect gastrointestinal function, including appetite and digestion. Due to renal insufficiency, patients with uremia may experience systemic symptoms such as fatigue, weakness and decreased overall sense of health, which may also affect appetite.

Loss of appetite, even nausea, vomiting and other digestive system manifestations are common and early symptoms in patients with uremia. Some patients will go to the gastroenterology department first, which delays the treatment. We should learn a lesson from Lao Li's experience. Although chronic kidney disease is insidious, there are still some clues to follow. For example, patients with chronic kidney disease have immune dysfunction and long-term proteinuria excretion leads to loss of functional protein, and they are prone to colds. They may have morning facial edema, increased foam in urine, and increased nocturia. Some patients may have obvious symptoms such as hematuria, edema, and hypertension.

Lao Li's case reminds us that regular physical examinations and attention to body signals are essential for the prevention and early treatment of kidney disease. For any abnormal symptoms, such as persistent loss of appetite, nausea, edema, hematuria or increased nocturia, you should seek medical attention in time.