The gastric emptying rate of the human body decreases at night. If metformin extended-release tablets are taken at dinner, their retention time in the stomach will be relatively prolonged, which is conducive to maintaining the drug effect for a longer period of time. At the same time, since the blood concentration of metformin extended-release tablets reaches its peak about 7 hours after a single oral administration, taking it at night can effectively improve the blood sugar dawn phenomenon (morning blood sugar increase) of diabetic patients and lower fasting blood sugar levels. Of course, even if metformin extended-release tablets are taken in the morning or at noon, it is still effective. For example, for diabetic patients who have not satisfactorily controlled their blood sugar after taking 2000 mg, once a day, they can consider switching to 1000 mg, twice a day, with meals. |
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