Suppositories refer to solid preparations made of drugs and suitable matrices with a certain shape for administration into human cavities. Suppositories are solid at room temperature. After being inserted into the human cavity, they can quickly soften, melt or dissolve in the secretions at body temperature, gradually releasing the drugs to produce local or systemic therapeutic effects. They are generally stored in a cool, ventilated, and light-proof environment. Since suppositories are greatly affected by temperature, if the ambient temperature is too high, the suppositories will soften and melt. At this time, provided that the drug has not expired, it can be placed in the refrigerator (2℃~8℃) for a period of time until the melted suppository solidifies again and can continue to be used without affecting the efficacy of the drug. |
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