Diagnosis and treatment of intrahepatic cholestasis of pregnancy

Some of you may have heard of the symptoms of intrahepatic cholestasis of pregnancy, but there are definitely not many people who really understand it. However, since intrahepatic cholestasis of pregnancy is very harmful, it is still necessary for us to learn more about it. In the following article, we will introduce to you the diagnosis and treatment methods of intrahepatic cholestasis of pregnancy.

The diagnosis of intrahepatic cholestasis of pregnancy mainly relies on medical history, clinical manifestations and laboratory tests. Liver function and serum bile acid should be measured in a timely manner for suspected cases. The serum transaminase of pregnant women with this disease may be slightly or moderately elevated, with the increase being about 2 to 3 times the normal value. Increased serum bile acid is a sensitive indicator for diagnosing this disease. The increase can often be 10 to 100 times that of normal pregnant women. Moreover, the increase in serum bile acid occurs earlier than pruritus and jaundice. Therefore, many hospitals often routinely test serum bile acid at 28 to 30 weeks of pregnancy as a screening for intrahepatic cholestasis, so as to detect the disease early and take timely treatment measures. After the disease is diagnosed, drugs such as cholestyramine, phenobarbital or dexamethasone can be taken. The modified Chinese medicine Capillaris decoction also has a good therapeutic effect, which can reduce the level of bile acid in the blood and its adverse effects on the mother and child.

In addition to drug treatment, you should also pay attention to rest and lie on your left side to increase placental blood flow and improve fetal intrauterine hypoxia. And the fetal movements should be counted carefully, three times a day, morning, noon and evening, each time for 1 hour. Carry out prenatal examinations on time, strengthen fetal electronic monitoring and abdominal B-ultrasound examinations to monitor placental function and fetal condition. After 35 weeks of pregnancy, the patient should be hospitalized to monitor the safety of the fetus. If the fetus is found to be in danger in the uterus, timely treatment should be provided to rescue the fetus. After the pregnancy reaches 37 weeks, the pregnancy should be terminated in time to avoid the serious consequence of sudden intrauterine fetal death during the extended pregnancy. During delivery, fetal monitoring should be strengthened to prevent the occurrence of fetal distress and to prepare for neonatal rescue. For those with fetal distress or other high-risk factors, cesarean section may be performed to end delivery to ensure a good prognosis for the newborn.

In the above article, we introduced a relatively rare symptom, that is, intrahepatic cholestasis of pregnancy. We know that intrahepatic cholestasis of pregnancy is very harmful, so female friends should pay attention to this symptom. The above article introduces in detail the diagnosis and treatment methods of intrahepatic cholestasis of pregnancy.