Medicine Baby Quiz | The higher the grade of cephalosporin, the better the efficacy?

Cephalosporin antibiotics are currently divided into five generations based on their antibacterial spectrum, antibacterial effect, stability to β-lactamase, and nephrotoxicity.

Each generation of cephalosporins has its own antibacterial characteristics and advantages and disadvantages. For example, the first generation of cephalosporins has stronger antibacterial activity against Gram-positive bacteria than the second and third generation cephalosporins, but has certain toxicity to the kidneys. The third generation of cephalosporins has stronger activity against Gram-negative bacteria, is effective in treating intestinal, urinary tract and abdominal infections, and has less renal toxicity, but is not better than the first generation of cephalosporins in most cases for treating common community-acquired respiratory infections.

Therefore, the choice of cephalosporin antibiotics to treat infections should vary from person to person, and one should not blindly assume that the higher the level, the better the effect.