[Fat Bear Science] Did you know? Experts say that people with these diseases have a cancer risk many times higher than the general population. The truth is...

In recent years, with the increasing incidence of malignant tumors, it has gradually become the number one killer of human health, and endocrine metabolic diseases such as diabetes and thyroid disease are also severely affected areas. There are more than 100 million diabetes patients alone.

"There is a close connection between malignant tumors and various endocrine and metabolic diseases such as diabetes, thyroid disease, and abnormal bone metabolism, but cross-disciplinary cooperation between the two disciplines is rare in China," said Wu Qinan, head of the Department of Endocrinology and Nephrology at the Affiliated Cancer Hospital of Chongqing University.

First of all, many cancer patients suffer from endocrine tumors, such as thyroid cancer, pituitary tumors, adrenal tumors, etc. The development and metastasis of some tumors are also related to endocrine hormones, such as breast cancer and prostate cancer related to sex hormones.

Secondly, with the improvement of tumor diagnosis and treatment and the significant extension of survival time, many patients with non-endocrine tumors may develop a variety of endocrine and metabolic complications.

Finally/with the advancement and updating of treatment methods, anti-tumor drugs lead to many adverse endocrine and metabolic reactions such as thyroid dysfunction, blood sugar disorder, abnormal bone metabolism, adrenal dysfunction, pituitary dysfunction, sexual dysfunction and electrolyte disorder.

"Taking tumors and diabetes as an example, a large amount of research and data has confirmed that diabetic patients have a higher risk of developing malignant tumors." Wu Qinnan said that the more common malignant tumors in diabetic patients include liver cancer, kidney cancer, pancreatic cancer, rectal cancer, bladder cancer and lung cancer.

Research surveys have shown that male diabetic patients are 27% more likely to develop cancer than men without diabetes, and respondents with fasting blood sugar levels higher than 7.8mmol/L are 25% more likely to die from cancer than those with fasting blood sugar levels lower than 5.6mmol/L.

Malignant tumor treatment drugs, radiotherapy, and immune checkpoint inhibitors may also increase the incidence of diabetes. At the same time, patients with tumor-related diabetes have a lower blood sugar control rate and a worse prognosis than those with ordinary diabetes.

"Therefore, it is very necessary to open a tumor endocrinology clinic and establish a tumor endocrine MDT in the future." Wu Qinnan said that this has practical significance for standardizing the risk assessment and diagnosis and treatment of tumor endocrine patients, solving the clinical problems of difficult and serious tumor endocrine patients, and treating patients with malignant tumors more accurately.

As a Class-A tertiary tumor hospital, the Affiliated Cancer Hospital of Chongqing University features tumor diagnosis and treatment, while retaining endocrinology as a basic discipline, and has unique conditions in China.

Which patients should see a doctor?

Wu Qinan said that two types of cancer patients need:

■ Patients with endocrine and metabolic diseases caused by tumor treatment, such as elevated blood sugar and electrolyte imbalance;

■ Tumor patients have combined endocrine and metabolic diseases such as diabetes, hyperthyroidism, etc.

Wu Qinan said that as an emerging discipline, future development faces many challenges: innovation and change of concepts, urgent transformation of diagnosis and treatment models, strengthening of training of tumor endocrinology specialists, urgent strengthening of related research in tumor endocrinology, and good collaboration among multiple disciplines in the discipline of tumor endocrinology.

At the same time, it is also full of opportunities and hope. The Affiliated Cancer Hospital of Chongqing University will actively explore tumor endocrine diagnosis and treatment models, promote the development of tumor endocrinology, strengthen multidisciplinary and multi-center cooperation, closely integrate the latest developments in related fields, and set reasonable evaluation and intervention strategies.

Introduction to Endocrinology and Nephrology

The Department of Endocrinology and Nephrology of Chongqing Cancer Hospital/Affiliated Cancer Hospital of Chongqing University integrates medical treatment, scientific research and teaching, and is committed to the prevention, diagnosis, treatment, rehabilitation and education of endocrine metabolic diseases and kidney diseases.

Staffing

There are more than 20 medical staff members, including 2 deputy chief physicians, 4 attending physicians, 3 with doctoral degrees, and the rest with master's degrees in the medical series; more than 80% of the nursing series have bachelor's degrees.

Academic Team

The Department of Endocrinology and Nephrology is a team with a reasonable talent structure, high clinical research level and positive attitude. The department is currently a member of the Osteoporosis and Bone Mineral Disease Committee, Endocrinology Committee, Diabetic Foot Group, Thyroid Group, Adrenal Gland and Secondary Hypertension Group of Chongqing Medical Association, a member of the Diabetes Committee of Chongqing Association of Integrated Traditional Chinese and Western Medicine, and a member of the Chongqing Branch Committee of Fatty Liver Alliance. It is also a member and secretary-general of the Endocrinology and Diabetes Youth Committee of Chongqing Medical Association.

Scientific research achievements of department staff

Wu Qinan, doctor of medicine, associate chief physician, associate professor, is currently the head of the Department of Endocrinology and Nephrology of the Affiliated Tumor Hospital of Chongqing University. He has been engaged in clinical and basic research in endocrinology for many years. His research direction is the pathogenesis and prevention of diabetes and its complications. He is a member of the Osteoporosis and Bone Mineral Disease Committee of Chongqing Medical Association, a member of the Diabetic Foot Group of the Diabetes Committee of Chongqing Medical Association, a member of the Youth Committee and Secretary-General of the Diabetes Committee of Chongqing Medical Association, a member of the Diabetes Committee of Chongqing Association of Traditional Chinese and Western Medicine, a member of the Chongqing Expert Committee of Fatty Liver Alliance, an editorial board member of Biomedical Research & Experimental Sciences and Journal of Peer Scientist, a subject editor of Annals of Translational Medicine, a guest editor and reviewer of the Journal of Chongqing Medical University, a young and middle-aged editorial board member of Clinical and Pathological Medicine, a special editor of the Chinese Journal of Clinical Physicians (electronic version), and an expert opinion on Therapeutic Targets, Diabetes Research and Clinical Practice, Life Science, Journal of Diabetes Research, Journal of Thoracic Disease, Chinese Journal of Hypertension, Journal of Central South University (Medical Edition), presided over 7 scientific research projects of Chongqing City, Chinese Medical Association, etc., published 11 papers in foreign SCI journals as the first (co-first) author, published more than 20 papers in domestic core journals, obtained a national invention patent, and won a second prize for military medical achievements.

Clinic hours: Monday and Wednesday all day

Scope of diagnosis and treatment and characteristics

The department consists of 1 ward, 1 blood purification center and 1 instrument inspection room, and is currently establishing a national standardized metabolic disease management center.

The ward has 53 beds and is equipped with a real-time dynamic insulin pump, a dynamic blood glucose monitoring system, a dual-energy X-ray bone densitometer, a blood gas analyzer, a body fat analyzer, an ophthalmoscope, a peripheral vascular diagnostic system, a sensory nerve quantitative tester, a transcutaneous oxygen partial pressure, a diabetic foot diagnostic toolbox, a neurovascular therapeutic device, an osteoporosis therapeutic device, a hemodialysis machine, an ECG monitor, etc.

The department has a patient education team, blood sugar management team, diabetic wound management team, endocrine and metabolic critical care management team and kidney disease team.

The diagnosis and treatment projects offered include: diabetes and acute and chronic complications (diabetic ketoacidosis/hyperosmolar state, diabetic foot, diabetic nephropathy, peripheral neuropathy/vascular disease and retinopathy, etc.), thyroid diseases (including hyperthyroidism, hypothyroidism, thyroiditis, thyroid nodules, etc.), osteoporosis, gout, dyslipidemia, obesity, electrolyte disorders, pituitary diseases, adrenal diseases, sexual development diseases, acute and chronic nephritis, acute and chronic renal failure, urinary tract infections, etc. In particular, the diagnosis, treatment and management of tumor-related endocrine kidney diseases are formed in combination with the oncology specialty, which is unique in the country and Chongqing.

The Department of Endocrinology and Nephrology is a medical team with innovative scientific research thinking, superb clinical skills, and rich clinical teaching experience. The department adheres to the concept of "benevolent skills to regulate secretion balance, and benevolent heart to promote metabolic harmony" and is dedicated to providing high-quality and warm services to the majority of patients.

Address: 8th Floor, Internal Medicine and Technology Building

Tel: 023-02365070534 (Doctor's Office) 023-65070533 (Nurse Station)

Text/ Fat Bear Photos/ Internet (please contact to delete) Review/ Wu Qinan

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