It is not only cephalosporin antibiotics that can produce "mixed poison" with alcohol, but also these drugs

Huazi was having dinner with her colleagues. When everyone had just finished their first glass of wine, one of them suddenly stood up and ran out, muttering, "It's bad, it's bad." After a while, she returned to the banquet, but her face was pale. Everyone asked her what happened. She said that her tonsils were inflamed and she had been injected with cefoperazone for several days, but she forgot about it when she was drinking just now. She remembered it after the wine went into her stomach, so she hurried to the bathroom to induce vomiting.

The table was immediately filled with jubilation. As a pharmacist, he actually made such a "low-level mistake". If he was really sent to the hospital for emergency treatment because of "mixed poison" caused by drinking after taking cefuroxime, his colleagues in the emergency room would definitely laugh at him.

1. Do not drink alcohol after taking cephalosporin antibiotics. This is because cephalosporin can inhibit the alcohol decomposition enzyme in the human body, so that the alcohol you drink cannot be completely decomposed, resulting in poisoning. Even if you could drink a thousand cups without getting drunk before, under the effect of cephalosporin, you will experience symptoms such as headache, dizziness, abdominal pain, drowsiness, low blood pressure, hallucinations, etc., and severe cases may be life-threatening.

So people made a rhyme about the "mixed poison" that cephalexin and alcohol would produce when mixed together, "Cephalexin with alcohol, the result is just like that."

However, in addition to cephalosporins, there are other drugs that can produce the same reaction. For example, metronidazole, tinidazole, ornidazole, which are often used to treat toothaches, furazolidone for treating diarrhea, ketoconazole and griseofulvin for treating fungal infections, and sulfamethoxazole in the sulfonamide class of drugs all have the same effect as cephalosporins. When combined with alcohol, this life is gone.

2. There are many other drugs that cannot be taken with alcohol. 1. Psychotropic drugs: Alcohol itself is a sedative, which will enhance the central inhibitory effect of sedatives, hypnotics, antidepressants, and antipsychotics. Chaplin, one of Huazi's favorite comedy masters, fell into a long sleep because he took sleeping pills after drinking. Therefore, it is forbidden to drink alcohol when taking drugs such as phenobarbital, zopiclone, diazepam, and risperidone.

2. Drugs that irritate the stomach: Alcohol can irritate the gastric mucosa and increase the side effects of drugs that irritate the stomach. For example, drinking alcohol while taking aspirin, indomethacin, or ibuprofen can easily cause gastric ulcers and gastric bleeding. We have a saying in Northeast China, "If you want a strong relationship, drink until your stomach bleeds." But this is an exaggeration, so don't take it seriously. Because our bodies are not made of iron, your wallet will really bleed when you treat an illness.

3. Hypoglycemic drugs: People with diabetes cannot drink alcohol, because alcohol can increase the effects of hypoglycemic drugs such as glibenclamide, glimepiride, gliquidone, insulin, etc., causing hypoglycemia, while inhibiting the central nervous system, making it easy to fall into a coma. Normal people drink and get drunk, and they lie down and fall asleep, but it doesn't matter if they wake up. However, hypoglycemia coma is life-threatening. Diabetic patients also lie down and fall asleep when they are drunk, but they may not wake up for a long time and be cremated directly into ashes.

4. Chemotherapy drugs: Cancer patients undergoing chemotherapy should not drink alcohol, because alcohol can damage liver function and weaken liver metabolism. Drinking alcohol while using chemotherapy drugs such as fluorouracil and methotrexate can cause liver toxicity and neurotoxicity. Chemotherapy should have been very effective for many patients, but after drinking alcohol, before the drugs "killed" the cancer cells, their bodies could not bear it, and they would eventually lose the battle against cancer.

5. Antihypertensive drugs: Alcohol can increase heart rate and blood circulation, which can weaken the effect of antihypertensive drugs. If patients with hypertension drink alcohol, their blood pressure will rise, which can easily induce hypertensive encephalopathy and myocardial infarction. In order to help patients with hypertension remember the harm of drinking, Huazi made up a jingle, "High blood pressure is not scary, you can control it with medicine. If you drink a little wine, all the medicine you take will be in vain."

The drugs mentioned above are only a small part of the drugs that interact with alcohol. There are many more drugs that react with alcohol. In general, there are two interactions between drugs and alcohol: one is to reduce the efficacy of drugs, and the other is to increase adverse drug reactions. Finally, Huazi summarizes that if you want to live longer, try to drink less, don't take medicine when drinking, and don't drink when taking medicine.