Chromosomal abnormalities in women

Chromosomal abnormality is generally a more complicated disease, and there are many causes of chromosomal abnormality. In addition to congenital genetic causes, a person's environment and the substances they frequently come into contact with are also related to chromosomal abnormalities. At present, both men and women have a greater chance of having chromosomal problems, but the causes of chromosomal abnormalities vary according to gender. So what are the causes of chromosomal abnormalities in women?

Causes of Chromosomal Abnormalities in Women

1. Physical factors: the radiation environment in which humans live, including natural radiation and artificial radiation. Natural radiation includes cosmic radiation, earth radiation and radiation from radioactive substances in the human body. Artificial radiation includes radiation radiation and occupational exposure.

2. Chemical factors: People are exposed to various chemical substances in daily life, some of which are natural products and some are artificially synthesized. They can enter the human body through diet, breathing or skin contact, and cause chromosomal abnormalities.

3. Biological factors: When cells in culture are treated with viruses, various types of chromosomal aberrations often occur, including breakage, fragmentation, and exchange.

4. Maternal age effect: When the fetus is 6-7 months old, all oogonia have developed into primary oocytes and entered the nuclear reticulum stage from the prophase of the first meiotic division. At this time, the chromosomes are loosened and stretched again, just like the previous nucleus, and remain so until before ovulation in puberty. This state may be related to the synthesis of yolk.

5. Genetic factors: Chromosomal abnormalities can often show a familial tendency, which suggests that chromosomal abnormalities are related to genetics.

6. Autoimmune diseases: Autoimmune diseases seem to play a role in chromosome nondisjunction. For example, there is a close correlation between increased primary thyroid autoimmune antibodies and familial chromosomal abnormalities.

I believe everyone has a certain understanding of the causes of chromosomal abnormalities in women. We must pay attention to prevention in daily life, because once chromosomal abnormalities occur, the treatment is extremely difficult, and it may also affect the next generation, which is a very troublesome thing. Especially during pregnancy, women should pay more attention to the condition of chromosomes and have timely prenatal check-ups.