Breast granuloma is generally a proliferative reaction to mastitis. There are many causes of this type of granuloma mastitis. In addition to being related to autoimmune diseases, it may also be related to allergic reactions caused by milk blockage during lactation. Long-term chronic reactions can easily lead to the formation of granulation tissue. At this time, timely treatment is required. Let us learn about this aspect. Breast granuloma surgery recovery period Plasma cell mastitis and granulomatous mastitis usually recur within 3-5 months after surgery. There will be no recurrence after half a year, and the disease will occur on the contralateral side in the future. Therefore, you should come back for a follow-up check at least once within 3 months to 6 months after the operation. In the past, we advocated a follow-up examination three months after surgery, but some people had local recurrence in May, so now the follow-up time has been postponed to six months. The disease may still occur on the other side after 3 years, so a follow-up examination should be conducted at least once a year after surgery. Causes of granulomatous mastitis 1. Autoimmune diseases: local immune phenomena and local hypersensitivity reactions caused by breast milk. Non-bacterial infection associated with the use of oral contraceptives. It may also be related to infection, trauma, and chemical stimulation that causes inflammation, destroys the ductal epithelium, and allows the contents of the cavity to enter the lobular interstitium, causing granulomatous reactions and further destroying the lobular structure. It is common in married and multiparous women of childbearing age. 2. It may be due to the reverse escape of milk, secretions and keratinized epithelium in the duct into the lobular interstitium, causing local inflammatory and hypersensitivity reactions, leading to the formation of granulation tissue. 3. Microabscesses, epithelial macrophages and foreign body granulomas can be seen in the lesions. It is believed that the disease is caused by local infection, trauma and inflammation caused by chemical substances. The ductal epithelium is destroyed due to inflammatory damage, and the contents of the ductal cavity enter the lobular interstitium, causing granulomatous inflammation. Treatment principles The treatment of GM is controversial. Among the current treatment methods, traditional simple surgical resection accounts for about 50%, with a recurrence rate of up to 20% to 30%. Surgery after steroid hormone treatment can reduce the recurrence rate. Hormone plus immunosuppressant treatment and anti-mycobacterial treatment also have obvious effects. When GM presents as a mass as the main manifestation, it resembles breast cancer, so the treatment opinions are basically unified. Classification and treatment should be implemented only after the diagnosis is confirmed by CNB or surgical biopsy and a comprehensive assessment of the condition is made. It is mainly based on the cause, severity of the disease, prolactin level, whether there is infection with Corynebacterium, the scope of the lesion and other associated diseases, and is treated according to the mass type, abscess type (including mass plus abscess) and refractory GM. |
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