What is the critical risk of early Down syndrome screening?

What is the critical risk of early Down syndrome screening?

Down syndrome is a serious developmental malformation that can also cause intellectual damage, causing the child to be born with both deformity and intellectual disability. This disease is caused by a combination of factors, and people should try to avoid this symptom in their lives. Therefore, it is very necessary for pregnant women to undergo regular early Down syndrome screening. What is the critical risk of early Down syndrome screening?

When the blood test screening value is greater than 1/270, it means that the person is in a high-risk group, and the normal value is around 1/700. The international standard is 1/270 and the Down syndrome screening value is a revised value.

Down syndrome screening is mainly for screening Down syndrome, that is, to check whether the baby will be a congenitally stupid Down syndrome baby, mainly checking alpha-fetoprotein, human chorionic gonadotropin, and free estriol.

Fetuses with Down syndrome are not exclusive to older pregnant women. Although older pregnant women over 35 years old are closely related to Down syndrome, the older the age, the greater the chance of giving birth to a child with Down syndrome. However, young women may also give birth to children with Down syndrome, and only 20% of Down syndrome occurs in older pregnant women, while the other 80% of Down syndrome fetuses are born to young pregnant women under 35 years old. Therefore, if only older pregnant women are examined, it will not be a good way to prevent Down syndrome.

On the other hand, if all pregnant women undergo amniocentesis or chorionic villus sampling, not only will the cost be higher, but it will also increase the chance of miscarriage, so it is not necessary for all women to undergo amniocentesis or chorionic villus sampling. Currently, the best way to prevent Down syndrome is: all young pregnant women undergo Down syndrome screening tests, and those who are shown to be at high risk will undergo amniocentesis or chorionic villus sampling. Through amniocentesis or chorionic villus sampling, it can be determined whether the fetal chromosomes are normal and whether the fetus has Down syndrome.

Extracting amniotic fluid: 20 ml of amniotic fluid is collected. The risks are possible infection, amniotic fluid leakage, miscarriage, and the possibility of miscarriage (probability 1/1000). Guidance:

If you want to confirm the diagnosis, you need to do amniocentesis, which is to extract a small amount of amniotic fluid for examination under B-ultrasound positioning. It generally will not cause adverse effects on you and your baby.

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