What to do if the corpus luteum is insufficient after ovulation

The corpus luteum is a structure that every female has in her body. It is very important to our human body, but it often has some problems. Each of us has an ovulation period, and after ovulation, there may be a situation of insufficient corpus luteum. This situation can be solved in some ways. So what should we do if there is insufficient corpus luteum after ovulation?

The corpus luteum is a vascularized gland-like structure that is rapidly transformed from the ovarian follicle after ovulation.

After ovulation, the remaining follicular wall collapses, and the connective tissue and capillaries of the follicular membrane extend into the granulosa layer. Under the action of LH, it evolves into a larger cell cluster rich in capillaries and with endocrine function. It appears yellow when fresh and is called corpus luteum.

Progesterone supplementation therapy: 25 mg of progesterone vaginal suppository is inserted deep into the vagina or rectum, once in the morning and once in the evening, for self-use by the patient. It starts 2 days after the basal body temperature rises (the 16th or 17th day of the menstrual cycle) and ends when menstruation occurs.

Progesterone oil: 10 mg intramuscularly injected daily, or 20 mg intramuscularly injected every other day, used from the second day after the basal body temperature rises.

Synthetic progestin: 2 mg of progesterone acetate, 3 times a day, or 5 mg every night. Start taking the medicine 2 days after the basal body temperature rises.

Human chorionic gonadotropin (hcg) therapy: It can induce ovulation when used before ovulation, and can stimulate corpus luteum development, support corpus luteum function, increase progesterone synthesis, and prolong corpus luteum life when used after ovulation. The usage is to inject hc g 2000-3000u intramuscularly every other day starting from 3-4 days after ovulation, for a total of 3-4 times; or to inject 1000u intramuscularly every day starting from 3 days after ovulation, for 7-8 consecutive days.

Clomiphene therapy: The use of clomiphene to induce ovulation has been found to have poor luteal function in some patients. However, there are reports that for patients with natural ovulation, especially when progesterone supplementation therapy is ineffective, taking clomiphene 50 mg daily in the early follicular phase, that is, from the third day of the menstrual cycle, for 5 consecutive days can increase the pregnancy rate.

Bromocriptine therapy: Infertile patients with luteal dysfunction accompanied by elevated serum prolactin can be treated with bromocriptine: 1 to 2 times a day, 25 mg each time.