Can I get pregnant if I have Ureaplasma urealyticum?

Ureaplasma urealyticum is not often mentioned in daily life, but it does touch the hearts of many people all the time. Because many studies have found that ureaplasma is a factor that may affect sperm motility, many people worry that ureaplasma will affect pregnancy. In fact, as long as the disease is discovered in time, medical treatment is sought, and appropriate treatment is chosen, it can be cured soon.

1. So what impact does Ureaplasma urealyticum have on pregnancy? Will it cause miscarriage?

Although there is a lot of evidence that ureaplasma urealyticum can cause intra-amniotic infection. However, a multicenter clinical study conducted in the United States in the last century showed that vaginal colonization of Ureaplasma urealyticum during mid-pregnancy was not significantly associated with low birth weight, premature rupture of membranes, and premature delivery.

Therefore, most clinical studies believe that there is no need for intervention and treatment for patients with Uu detected in the lower reproductive tract during pregnancy.

Many clinical studies have shown that ureaplasma may affect sperm motility. The reason may be that mycoplasma adhesion affects sperm motility, or it may be that mycoplasma induces the production of anti-sperm antibodies. There is a correlation between mycoplasma and sperm motility, but its pathogenicity has not been clearly determined.

Many studies have shown that positive Uu culture in the reproductive tract of both men and women has no significant effect on the fertilization rate, abnormal fertilization rate, cleavage rate, clinical pregnancy rate and abortion rate of in vitro fertilization. It is believed that positive cervical ureaplasma urealyticum does not affect the pregnancy outcome of in vitro fertilization and embryo transfer.

2. If urogenital mycoplasma is detected, should it be treated or observed?

1. If both men and women have no symptoms related to urogenital tract infection and only Uu is positive, they are considered to be carriers and do not need treatment.

2. If the symptoms and signs of Uu disappear after infection treatment and only the Uu laboratory test result is positive, it should be considered whether the patient has become a Uu carrier and there is no need to continue drug treatment.

3. If a man is diagnosed with Uu urethritis, it is recommended that his sexual partner be treated at the same time, and he should avoid unprotected sex during treatment.

4. When a man has abnormal semen quality and wants to have children, it is recommended that both men and women receive a course of treatment at the same time.

5. If Mycoplasma genitalium testing is available, Mg testing should be performed proactively when urethritis and cervicitis are suspected.

6. Pregnant women who are diagnosed with Uu in the lower reproductive tract during pregnancy do not need intervention or treatment.

7. When treating pelvic inflammatory disease, it should be considered that mycoplasma may be involved in the pathogenesis of pelvic inflammatory disease, and the antibacterial spectrum should cover mycoplasma.

3. What is the treatment plan for mycoplasma infection?

Because mycoplasmas do not have cell walls, antibiotics such as lactams and glycopeptides that act on the cell wall are ineffective against mycoplasmas. Antibiotics that inhibit protein synthesis are effective against most mycoplasmas.

Common treatment regimens for urogenital mycoplasma infection are: doxycycline 100 mg, orally, twice a day, for 7 consecutive days; azithromycin 1 g, orally, once a day, or 0.25 g, orally once a day, double the first dose, for 5 to 7 days; levofloxacin 500 mg, orally once a day for 7 consecutive days; moxifloxacin 400 mg, once a day, for 7 to 14 days.

If the patient has pelvic inflammatory disease, treatment should be carried out according to the pelvic inflammatory disease treatment plan, with a total treatment course of 14 days.