What are the functions and effects of oxytocin?

What are the functions and effects of oxytocin?

Many people may not have heard of oxytocin, but they must have heard of oxytocin. In fact, oxytocin is oxytocin, which is a synthetic drug. In clinical practice, oxytocin is mainly used to help induce labor. Some women will experience weak uterine contractions before giving birth, which can lead to delayed birth of the child. At this time, you can consider injecting oxytocin into the mother. The following is a detailed introduction to the role and efficacy of oxytocin.

First, indications

Used for induction of labor, acceleration of labor, postpartum hemorrhage and incomplete uterine involution; nasal drops for promoting lactation; oxytocin provocation test.

Second, Usage and Dosage

Due to different dosage forms and specifications, please read the drug instructions carefully or follow the doctor's instructions for usage and dosage.

Third, adverse reactions

(1) There are fewer adverse reactions, including rare allergic reactions, and occasional nausea, vomiting, and hypotension.

(2) Large doses can cause tonic contraction of the uterus, compress the blood vessels of the uterine muscle layer, block the blood flow to the placenta, and cause fetal suffocation or uterine rupture. Therefore, the dosage and intravenous infusion rate must be strictly controlled.

Fourth, contraindications

It is contraindicated for patients who are allergic to this product, multiparous women with more than three children (prone to uterine rupture), patients with transverse position, narrow pelvis, obstructed birth canal, obvious cephalopelvic disproportion and abnormal fetal position, umbilical cord presentation or prolapse, complete placenta previa, vasa previa, fetal distress, excessive uterine contractions, obstetric emergencies requiring immediate surgery, or patients with uterine atony who have not responded to long-term medication.

Fifth, matters needing attention

(1) When used to induce labor, the indications must be clear to avoid danger to the mother and fetus. (2) During intravenous infusion, a drip rate regulator should be used to control the dosage. The drip rate should be determined according to the patient's specific condition. (3) If uterine contractions are weak, the injection time should not exceed 6 to 8 hours. (4) Use with caution in the following situations: abortion caused by termination of pregnancy with hypertonic saline, placental abruption, severe pregnancy-induced hypertension syndrome, heart disease, critical cephalopelvic disproportion, an enlarged uterus, a history of intrauterine infection, a history of dystocia caused by damage, surgical treatment of the uterus or cervix (including a history of cesarean section), cervical cancer, partial placenta previa, premature birth, unengaged fetal head, breech presentation, abnormal fetal position or presenting part of the fetus, and pregnant women over 35 years old. (5) The use of oxytocin during caudal block may cause severe hypertension or even cerebral vascular rupture. (6) The following items should be checked and monitored before and during medication: ① the frequency, duration and degree of uterine contractions; ② the pulse and blood pressure of pregnant women; ③ the fetal heart rate; ④ the uterine muscle tone during rest; ⑤ the maturity of the fetus; ⑥ the size of the pelvis and the descent of the fetal presenting part; ⑦ the balance of fluid intake and output, especially when oxytocin is used for a long time.

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