What causes hydatidiform mole?

What causes hydatidiform mole?

There are many reasons that can lead to hydatidiform mole. For example, if the activity of folic acid is very low, it may lead to severe folic acid deficiency during the formation of the embryo, which in turn may affect the synthesis of thymine, leading to embryonic death, or cause a lack of blood vessels in the embryonic villi, thus causing hydatidiform mole. In addition, if the consumption of carotene in the daily diet is very low, it may lead to an increased risk of hydatidiform mole. Here are some possible causes of hydatidiform mole.

Hydatidiform mole is divided into complete hydatidiform mole and partial hydatidiform mole, and complete hydatidiform mole is more common. Among them, nutritional status and socioeconomic factors are possible high-risk factors. People whose diets lack vitamin A and animal fats have a significantly increased risk of developing hydatidiform mole. Age is another high-risk factor, with women older than 35 and 40 or younger than 20 having a higher incidence rate. A history of hydatidiform mole in a previous pregnancy is also a high-risk factor. The chromosome karyotype of hydatidiform mole comes from the father, but the mitochondrial DNA comes from the mother. You can consider in vitro fertilization, selecting sperm with normal chromosomes to form a normal fertilized egg and implant it into the uterus.

It depends on where the hydatidiform mole grows. If it is under the serosa, the impact will not be too big. If it is in the mucosal layer, if it does not affect the menstrual volume or abdominal pain, you don't need to worry too much. If a cesarean section is used to give birth to a child, the hydatidiform mole can be removed at the same time. If it is not very serious, the hydatidiform mole will shrink after the woman stops menstruating because it is hormone-dependent. Hydatidiform mole, also known as vesicular pregnancy, can be found in any woman of childbearing age and is common in pregnant women aged 20-30. The exact cause of this disease is still unclear, but it is generally believed to be related to factors such as nutritional disorders (especially folic acid deficiency), infection (especially viral infection), genetics and immune dysfunction.

In fact, in addition to the causes of hydatidiform mole introduced above, hydatidiform mole may also be caused by infection, but this is only a guess by some researchers and has not yet been effectively confirmed. Secondly, some people may have endocrine disorders, which lead to imperfect ovarian function and eventually cause hydatidiform mole. This situation often occurs in women between the ages of 20 and 40.

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