How to delay ovarian aging?

How to delay ovarian aging?

Premature ovarian failure and ovarian aging are actually diseases that are not good for the patient's body. Once the patient has ovarian aging, it means that the patient's ovarian function has varying degrees of failure symptoms. Patients at this time often have symptoms of fatigue and decreased libido. There are even cases where patients experience amenorrhea before the age of 40 due to ovarian aging. How can women delay ovarian aging?

It is characterized by primary or secondary amenorrhea accompanied by increased blood gonadotropin levels and decreased estrogen levels, and is accompanied by a series of low estrogen symptoms of varying degrees such as hot flashes, sweating, facial flushing, decreased libido, etc. The average natural menopause age for women is 50 to 52 years old. There are differences in the menopause age among races and regions, but the absolute values ​​are not much different. Coulam et al. summarized the natural amenorrhea of ​​1,858 women and found that the incidence of POF in women under 40 years old was 1% and that in women under 30 years old was 1‰. POF accounts for 10%~28% of primary amenorrhea and 4%~18% of secondary amenorrhea. Xu Ling et al. found that the incidence of POF among women in Beijing was 1.8%. It can be seen that POF is not uncommon in clinical practice.

Because immune factors are a definite cause of premature ovarian failure, immunosuppressive treatment is effective for patients with premature ovarian failure who have evidence of immune factors. There have been multiple reports of pregnancy occurring during immunosuppressive therapy. However, van Kasteren's randomized controlled study found that adrenocortical hormones did not affect the responsiveness of the ovaries to gonadotropins, so he believes that previous reports of successful immunosuppressive treatment may just be a coincidence with the natural recovery of the ovaries. So far, there is no clear method to identify the role of immune factors in POF, nor is there a clear indication for immunotherapy and a standardized medication regimen. Immunosuppressive therapy can cause serious side effects, so blindly using immunosuppressants to treat POF is not recommended clinically. In a randomized double-blind controlled study in 2007, 58 patients with idiopathic premature ovarian failure were randomly divided into two groups: the study group was GnRHa + Gn + dexamethasone (29 cases) and the control group was GnRHa + Gn + placebo (29 cases). Six women in the dexamethasone group ovulated (20.7%), while three women in the placebo group ovulated (10.3%). There were 2 singleton pregnancies in the dexamethasone group. Dexamethasone was used with no other discomfort except for a little drowsiness and fatigue. Conclusion: For patients with premature ovarian failure with normal chromosomal karyotype, ovulation induction therapy with dexamethasone and pituitary downregulation may be beneficial for the recovery of ovarian function.

To delay ovarian aging, you need to have a good attitude. Don't feel depressed just because you have uncomfortable symptoms. You need to have a peaceful mind at this time. You need to have an optimistic attitude. Patients are advised to actively engage in moderate exercise. Yoga, Tai Chi and walking are all suitable exercises. If you persist in exercising for a long time, it can greatly improve the patient's tissue condition. But don't do strenuous exercise

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