Introduction to atypical endometrial hyperplasia

According to experts, "Endometrial hyperplasia has a certain tendency to become cancerous, so it is classified as a precancerous lesion." Under long-term observation, the vast majority of endometrial hyperplasia is a reversible lesion, or it is possible to maintain a persistent benign state. Only in a few cases may cancer develop after a longer time interval.

Treatment principles: The treatment of atypical endometrial hyperplasia must first determine the diagnosis and find out the cause of the atypical hyperplasia, whether there is polycystic ovary, functional ovarian tumors or other endocrine dysfunction. Those with any of the above conditions should receive targeted treatment. At the same time, symptomatic treatment can be started for atypical endometrial hyperplasia, using drug therapy or surgical treatment. Different considerations for different ages: ① Young people who are eager to have children should prevent over-diagnosis and over-treatment. It is not uncommon for endometrial hyperplasia to be overdiagnosed as adenocarcinoma and even overtreated. It would be a serious mistake to remove the uterus without a clear diagnosis. In clinical practice, there are many examples of such mistakes. If the pathologist is not aware of the patient's fertility desire and the clinician does not emphasize it, misdiagnosis and mistreatment may be inevitable. Therefore, for the diagnosis of endometrial biopsy in young infertile women, if any doubt is found, multiple experts should be consulted to clarify the differential diagnosis of endometrial hyperplasia or endometrial adenocarcinoma to the greatest extent possible.

② Perimenopausal or postmenopausal women should be alert to the possibility of atypical endometrial hyperplasia and cancer coexisting, and should consider hysterectomy. Be careful not to be overly conservative and do not perform endarterectomy alone without ruling out the possibility of cancer, which may lead to adverse consequences. When the uterus is removed due to atypical endometrial hyperplasia, the removed uterus should be examined on the operating table to see if there is any co-existing cancer, and attention should be paid to whether there is any cancer infiltration into the muscle layer so as to select the appropriate surgical scope.

(2) Different types of intimal hyperplasia have different treatment principles.

This is all we have to say about atypical endometrial hyperplasia. Based on the above introduction, we understand that there are certain conditions for endometrial hyperplasia to develop into uterine cancer. Therefore, there is no need to worry about cancer, as this only happens to very few patients. As long as everyone pays more attention on weekdays and maintains a normal schedule, it will be enough.