Is non-invasive DNA testing necessary?

The 18th week of pregnancy is a critical period for pregnant women to conduct fetal anomaly screening, and minimally invasive surgical DNA testing is one of the key methods of fetal anomaly screening. Minimally invasive surgical DNA testing is also known as minimally invasive surgical prenatal DNA testing, minimally invasive surgical fetal chromosome aneuploidy testing, etc. The minimally invasive DNA prenatal examination only requires the collection of venous blood from the pregnant mother, and the use of the next-generation DNA sequencing technology to sequence the free DNA fragments (including fetal free DNA) in the jugular vein blood of the pregnant mother. The sequencing results are then analyzed for microbial status, from which the genetic information of the fetus can be obtained, and then whether the fetus suffers from the three major chromosome symptoms. So which 6 types of expectant mothers must do this?

1. Pregnant women who have experienced a history of spontaneous abortion, malformed babies, fetal death or stillbirth should undergo minimally invasive prenatal DNA testing when they become pregnant again.

2. If one of the spouses is a chromosomal patient, minimally invasive prenatal DNA testing is required. Minimally invasive prenatal DNA testing can detect all chromosomal aneuploidy cases and can very well detect chromosomal abnormalities in the fetus.

3. Pregnant women who have been pregnant or given birth to patients with sex chromosomes need to undergo minimally invasive prenatal DNA testing. According to relevant data, pregnant women who have had chromosomal symptoms before are more likely to have sex chromosome symptoms when they get pregnant again than ordinary people.

4. Women who refuse any trauma examination due to concerns about risks such as miscarriage. Some pregnant mothers worry that tests such as amniocentesis may have a certain impact on the fetus. Therefore, they are concerned about conducting tests such as amniocentesis at will.

5. For those who have abnormal fetal ultrasound results, minimally invasive prenatal DNA testing is required.

6. One of the spouses has a history of contact with materials related to malformed fetuses. If one of the spouses often has to work in an environment with radioactive substances, it is more likely to cause a baby with Down syndrome. Therefore, it is more necessary to undergo minimally invasive prenatal DNA testing.

In general, every couple is at the risk of having a baby with a chromosomal disorder. The disease is accidental and random, with no prior signs, and the incidence rate increases with the age of the pregnant mother. Especially for the above-mentioned pregnant women who are at high risk of having a fetus with Down syndrome, minimally invasive prenatal DNA testing is indispensable. Minimally invasive prenatal DNA testing is accurate, safe, minimally invasive, and can detect symptoms of chromosomal abnormalities in the early stages. It can detect all aneuploid chromosome abnormalities very well.