What are the dangers of ketosis in pregnant women

During pregnancy, pregnant women become the key protected objects in the family because of their special physical constitution. As key protected objects, they should not only pay attention to their physical health, but also always do a good job of pregnancy check-ups. Many pregnant women often suffer from diabetes, high blood pressure, cardiovascular and cerebrovascular diseases during pregnancy. Severe cases may also lead to ketone bodies. If there are ketone bodies in the body of a pregnant woman, the harm is very serious and may cause severe vomiting, purpura and digestive dysfunction. The harm caused is enough to cause the patient to go into coma and shock, and the physical constitution and immune function begin to decline on a large scale. Therefore, the harm of ketone bodies in pregnant women needs to be carefully prevented.

Ketone body positive may be the following :

1. In diabetic patients or those suffering from diabetic acidosis, a strong positive result (+++ or above) will appear. At this time, attention should be paid as toxic coma may occur easily and treatment measures should be taken promptly.

2. Severe vomiting, diarrhea, long-term malnutrition, hunger, and after strenuous exercise.

3. Pregnant women may suffer from severe vomiting, eclampsia, digestive and absorption disorders due to pregnancy reactions.

When your body cannot use glucose as an energy source, it will use fat to break down and produce energy. At this time, an acidic substance called ketone bodies will appear. If too much ketone bodies accumulate in the body, it will cause serious consequences, even coma. Therefore, people with diabetes, especially type 1 diabetes, should be able to self-monitor urine ketone bodies in order to promptly detect excessive accumulation of ketone bodies in the body.

Urine ketone bodies should be measured in the following situations :

*Please test your urine for ketones when the following situations occur:

Blood sugar over 240 mg/dl

When treatment is stopped for various reasons

Cold or illness

Suffering from infectious diseases

Before and After Surgery

Vomiting or stomach upset

Pregnancy

Extremely nervous

* Determination method - self-test of urine ketone bodies can be done by test paper method:

Insert the test strip into the urine sample.

Clinical significance

Ketone bodies vary in different types of metabolic acidosis. Metabolic acidosis usually results from one of the following: ① Increased production of organic acids such as β-hydroxybutyrate and acetoacetate associated with diabetes or alcohol or lactic ketoacidosis, such as can be seen in tissue perfusion disorders. Increased excretion of cations and ketone bodies in urine. ②HCO3- loss, for example: diarrhea caused by duodenal fluid loss. As the blood sodium concentration decreases, the blood chloride concentration usually increases. ③ Decreased acid excretion, such as as a result of renal insufficiency or renal tubular acidosis.

The criteria for evaluating metabolic acidosis are: ① Calculation of anion gap, the normal value is 8~16mmol/L, anion gap (mmol/L) = [Na+]-([Cl-]+[HCO3-]). ② Determine β-hydroxybutyrate and possible acetoacetate in serum or semi-quantitatively detect urinary ketone bodies.

(1) Metabolic acidosis with normal anion gap: This type of metabolic acidosis is associated with hyperchloremia. Possible causes include underlying renal tubular acidosis, carbonic anhydrase inhibitor ingestion, and hyperkalemic acidosis.

(2) Metabolic acidosis with increased anion gap: Metabolic acidosis caused by ketoacidosis, lactic acidosis, renal failure, salicylate poisoning and ethanol poisoning can cause normal or occasionally decreased blood chloride.

(3) Metabolic acidosis with increased anion gap and the presence of ketone bodies: Diabetes and alcohol are common causes. One in four cases of diabetic acidosis in intensive care units is caused by alcoholic ketoacidosis.