How is hydatidiform mole caused?

For patients with hydatidiform mole, if the condition has been diagnosed, it is often necessary to treat it through curettage. Some female friends may not have a particularly large uterus, and the contents of the hydatidiform mole are relatively small after the onset of hydatidiform mole. At this time, a single curettage can clean it up. If the contents are relatively large and the number of blisters is large, it is possible to metastasize and it may be difficult to clean it up with one curettage. At this time, you may need to consider two curettages.

It is believed that the occurrence of hydatidiform mole is related to the imperfect or declining ovarian function, so it is more common in women under 20 years old and over 40 years old. Animal experiments have shown that removing the ovaries in early pregnancy can cause vesicular changes in the placenta, so it is believed that estrogen deficiency may be the cause of hydatidiform mole. Racial differences in the incidence of hydatidiform mole have been noted. It has been reported that the incidence of hydatidiform mole in black women in the United States is only half that of other women. In Singapore, the incidence of hydatidiform mole in Eurasians is twice as high as that in Chinese, Indians and Malaysians.

Oncogenes and tumor suppressor genes are genes that control cell growth and differentiation. The activation and overexpression of oncogenes and the mutation and inactivation of tumor suppressor genes are related to the occurrence of tumors. Hydatidiform mole is more common in rice-eating countries, so it is believed to be related to nutrition. Studies have found that the activity of folic acid in the serum of patients with gestational trophoblastic tumor (GTT) is very low. Folic acid deficiency during the period of embryonic angiogenesis will affect thymine synthesis, leading to embryonic death and lack of blood vessels in the placental villi; low consumption of carotene in the diet increases the risk of hydatidiform mole; the incidence of hydatidiform mole increases in areas deficient in vitamin A; the content of trace elements Zn and Se in hydatidiform mole tissue decreases.

The above introduces some possible causes of hydatidiform mole. It should be noted here that the specific cause of hydatidiform mole is not particularly clear at present. This disease usually occurs in women around 20 to 40 years old. If you are unfortunately diagnosed with hydatidiform mole, you must actively seek medical examination and treatment. Do not engage in overly strenuous activities either before or after treatment.