What are the causes of endometriosis?

Endometriosis is a gynecological disease with a relatively high incidence rate. So what are the causes of endometriosis? This question is very necessary for female friends to understand. Next, this article will introduce to you the causes of endometriosis. Friends who are interested can take a look! Please see the detailed introduction below.

Endometriosis is a common gynecological disease in women caused by the implantation of endometrial cells in abnormal locations. Endometrial cells should grow in the uterine cavity, but because the uterine cavity is connected to the pelvic cavity through the fallopian tube, endometrial cells can enter the pelvic cavity through the fallopian tube and grow ectopically. There are many theories about the pathogenesis of this disease, among which the endometrial implantation theory is widely accepted. In addition, the occurrence of endometriosis is also related to the body's immune function, genetic factors, and environmental factors.

What are the causes of endometriosis?

1. Implantation Theory

Menstrual blood flows backwards and endometrial implantation occurs. During the menstrual period, menstrual blood flows downstream from the cervix and vagina. However, a small amount of menstrual blood or other reasons mixed with shed endometrial fragments flow into the abdominal cavity through the fallopian ducts and implant on the surface of the pelvic organs to form endometriosis lesions.

2. Metaplastic endometrium

Serosa epithelium, metaplastic intima. During the human embryonic development period, the ovarian surface epithelium, peritoneum, vaginal rectal diaphragm, and umbilicus are all derived from the metaplasia of the body cavity epithelium. These tissues can be transformed under the stimulation of gonadal hormones, inflammation, and mechanical factors to form another type of tissue, which can also metaplasia into the endometrium.

3. Benign metastasis

Hematolymph, benign metastasis. This is a relatively rare cause of the disease. Endometriosis that occurs in the lungs, meninges, pericardium, limbs, and other distant parts is caused by the transfer of endometrial debris through the blood circulation or lymphatic system and retention in certain organs or tissues.

4. Iatrogenic endometrial transplantation

This is an artificial process that causes the endometrium to be transplanted to certain parts of the uterus. It is common in cesarean sections, curettage in early and mid-term pregnancy, episiotomy during delivery, and artificial abortion.

5. Deficiency of immune defense function

The endometrium that flows back into the abdominal cavity with menstrual blood is like a foreign body. It will activate the body's immune system and mobilize a large number of immune cells and body fluids to encircle and eliminate it. If the body's immune function is defective, it will develop into endometriosis.

6. Endocrine dysfunction

The growth and changes of ectopic endometrium, regardless of its origin, are related to ovarian endocrine secretion. Estrogen can promote growth, while progesterone can inhibit it. Clinically, it has been found that most patients are deficient in progesterone, which contributes to the occurrence and development of this disease.

7. Genetic and physical factors

Clinical observations have found that people with a family history of the disease are more likely to suffer from this disease. Physical factors such as obesity, overweight, and height also have a certain relationship.

The above is an introduction to the causes of endometriosis. I believe that after reading this introduction, you will have an understanding of the causes of endometriosis. From the above we can know that there are many causes of this disease. Therefore, when this disease is discovered, it is best for patients to consult a doctor in time and do relevant examinations to find out the cause so that symptomatic treatment can be given.