Parkinson's disease dyskinesia, make it stop!

Recently, a patient with Parkinson's disease who had been ill for more than 10 years came to our hospital's neurology department for treatment. Unlike the typical symptoms of Parkinson's disease, her jaw and head kept twisting, her limbs were dancing, and she was unable to walk on her own. Huh? Isn't the typical symptom of Parkinson's disease a decrease in movement? Why would there be involuntary movements with increased movement?

Image source: Pixabay

It was learned that the patient had been taking anti-Parkinson's disease drugs for a long time. Six months ago, due to worsening symptoms, he increased the dosage of dopamine by himself. Later, he developed involuntary movements all over the body. He visited many local hospitals but the cause was not determined and the symptoms did not improve. Under the leadership of the neurology degenerative disease team, the patient was carefully examined, and a detailed treatment plan was formulated after a full discussion of the condition. The dosage of the drug that caused the dyskinesia was gradually reduced, and amantadine was increased to alleviate the dyskinesia symptoms.

After one week of slow medication adjustment, the patient's involuntary movements gradually decreased and stopped, and he was eventually discharged from the hospital by walking.

Popular Science in Progress

1 Definition

Dyskinesia in Parkinson's disease is an involuntary movement that may occur in patients with Parkinson's disease (PD) during treatment. The main symptoms include twisting, twitching, chorea or dystonia.

2 Types

3 Treatment

1. Adjust the drug dosage or change the drug to reduce the occurrence of dyskinesia.

2. Use a system that can release the drug continuously to maintain a steady level of dopamine.

3. Deep Brain Stimulation (DBS): DBS can be used as an effective treatment for patients who do not respond to drug treatment.

4. Physical therapy can improve the patient's motor function and alleviate the effects of dyskinesia.

4. Prevention

1. Early diagnosis and treatment of Parkinson's disease can delay disease progression.

2. Use medications rationally and avoid adjusting medication dosages on your own.

3. Healthy lifestyle: balanced diet, moderate exercise and adequate sleep.

Source: Chongqing Banan District Second People's Hospital

Audit experts: Zhang Ling, Bao Zhonghui

Statement: Except for original content and special notes, some pictures are from the Internet. They are not for commercial purposes and are only used as popular science materials. The copyright belongs to the original authors. If there is any infringement, please contact us to delete them.