Can't have children if B27 positive?

The full name of 27 is HLA-B27, and its scientific name is human leukocyte antigen B27. There are 92 human leukocyte antigens, each belonging to the A, B, C, D and DR5 domains. There are 42 HLA domains, and B27 is one of them. If B27 is positive, you may have ankylosing spondylitis, which is a rheumatic disease with a strong hereditary nature. So, does it mean that you cannot have children if the b27 test is positive?

B27 positive can give birth to children. Among patients with ankylosing spondylitis, the HLA-B27 positivity rate reaches 90%. Not all patients with positive B27 have ankylosing spondylitis. The onset of ankylosing spondylitis is related to abnormalities in the natural environment and medical immunology. Therefore, women who are B27 positive can still marry and have children, but there is also a chance of genetic inheritance. After pregnancy, you should actively check, have regular prenatal examinations, pay attention to diet, get enough rest, eat more fresh fruits and vegetables, and eat more protein-rich foods.

The expression of HLA-B27 antigen is highly correlated with ankylosing spondylitis. More than 90% of patients with ankylosing spondylitis express positive HLA-B27 antigen. The clinical symptoms of ankylosing spondylitis are similar to those of many diseases and are difficult to diagnose. Therefore, the test of HLA-B27 is of great significance in the diagnosis of ankylosing spondylitis. In general clinical medicine, when lumbosacral pain occurs and X-rays mainly show sacroiliitis, HLA-B27 is basically tested when ankylosing spondylitis is highly suspected.

The b27 test is only one of the blood tests for diagnosing ankylosing spondylitis. The doctor needs to make a comprehensive assessment based on the patient's medical history, physical examination and other auxiliary test results to diagnose ankylosing spondylitis. A high level of b27 only indicates that the probability of suffering from ankylosing spondylitis is high. Simply put, it is only one of the blood tests for diagnosing ankylosing spondylitis. If b27 is high and the patient's symptoms and other special test results are all high, ankylosing spondylitis can be diagnosed.