Can I have a baby while taking Entecavir?

According to clinical medical statistics, long-term poor control of hepatitis B is the main cause of liver cancer. This is mainly because the patients did not receive standardized treatment during the anti-HBV process, which led to further malignancy of hepatitis B and gradually turned into cirrhosis or even liver cancer. It is not difficult to see the necessity of safe and appropriate use of medications. Entecavir is basically suitable for all chronic hepatitis B patients. Its efficacy and safety factor have been unanimously recognized in clinical medicine and is widely used in clinical treatment. So, can you have a child while taking entecavir?

Entecavir is a drug used in clinical medicine to treat hepatitis B virus, mainly for antiviral treatment. It is generally not recommended to prepare for pregnancy while taking medications, as it may cause adverse effects on the fetus. Generally, you need to stop taking the medicine for 3 months before you can consider preparing for pregnancy, which is relatively more appropriate. During the medication period, if you accidentally become pregnant and really want to keep the child, it is recommended to carry out regular prenatal checkups and various fetal abnormality screening tests in the later stages.

Because the effect of drugs on fetal malformation rate is not relative, it is all relative and probabilistic issues. If you really want to keep it, do various fetal abnormality examinations in the middle and late stages. The main aspects of fetal anomaly screening are the following: the initial fetal anomaly screening test is the NT test at 12 weeks of pregnancy, the late stage is the sugar screening test at 15-17 weeks of pregnancy, and the minimally invasive DNA test at 18-22 weeks of pregnancy, and a series of tests such as four-dimensional color Doppler ultrasound and fetal anomaly screening at 22-28 weeks of pregnancy. If all the tested indicators are normal, the probability of fetal health is relatively high. If the fetal indicators are found to be abnormal through fetal screening, in this case, it is still necessary to consider terminating the pregnancy immediately to avoid adverse effects on the fetus.

Entecavir is mainly used to treat hepatitis B virus and limit its viral replication. It is best for men not to get pregnant while taking this drug, because considering whether their liver and kidney functions are normal, the drug may have potential effects on the fetus and cause the fetus's development to be restricted.

Entecavir is not recommended for use in pregnant women because it is a Class C drug for pregnancy. Certain IVF toxicity was observed in clinical trials, but there is no data on humans, so it is not recommended for use in pregnant women. According to the implementation recommendations of the Chronic Hepatitis B Prevention Manual for special families, pregnant women with hepatitis B need to adjust their antiviral medications. If it is confirmed that entecavir is taken orally for antiviral treatment during pregnancy, the treatment plan needs to be adjusted, and entecavir should be replaced with tenofovir, telbivudine and other pregnancy-level B drugs, so that pregnancy can continue.