Can Down's syndrome tell the gender of a baby?

The chance of having a child with Down syndrome does exist, which includes family inheritance, gene chromosome mutations of parents, and hidden inheritance in the body. Therefore, it is not only those who have children with Down syndrome in the family who have the chance of inheritance. Down syndrome screening is a necessary examination, which can also ensure the health of the mother and the baby in the belly. In addition, is it accurate to judge the baby's gender through Down syndrome screening?

Can Down syndrome tell the gender of a child?

Down syndrome screening generally involves drawing 2 ml of blood from the pregnant mother to test the concentrations of alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), free estriol (uE3) and PAPP-A (early Down syndrome) in the serum. The risk factor of having a child with Down syndrome is calculated based on the mother's due date, age, weight and gestational age at the time of blood collection, thereby helping the pregnant mother decide whether to undergo further examinations.

The online saying about Down syndrome screening value to determine gender:

1. When the mom value of AFP is greater than 1 and the mom value of hCG is less than 0.5, it is a boy.

2. When the mom value of AFP is less than 1 and the mom value of hCG is greater than 1, it is a girl.

3. When the hCG value is between 0.5 and 1, and AFP is greater than 1, it is a boy, and AFP is less than 1, it is a girl.

The function of human chorionic gonadotropin (HCG) is to assist the corpus luteum to develop from the fertilized egg in the early stages of pregnancy and produce progesterone until the placenta is formed. HCG is of great significance in perinatal science. It can be used to detect whether a pregnant woman has an ectopic pregnancy or the probability of the fetus suffering from Down syndrome. At present, there is no theory to support that HCG levels can predict the sex of the fetus.

Alpha-fetoprotein AFP is a highly specific and sensitive tumor marker for primary liver cancer. Its levels will increase to varying degrees in pregnant women, and will decrease as the gestational age increases. Currently, there is no theory to support that the value is related to the sex of the fetus.

Therefore, the statement that the Down syndrome screening test value can determine the gender of the baby is unreliable!