Can anemia cause miscarriage?

If anemia occurs, it will definitely increase the chance of miscarriage to a certain extent. Therefore, female friends must make sure that their body is suitable for pregnancy before conceiving. If you already have anemia, you must seek treatment in time. Generally speaking, anemia is caused by excessive hyperfunction of your lymphocytes, so you should pay special attention to this.

Iron deficiency anemia, trauma, tumor, tuberculosis, bronchiectasis, peptic ulcer, liver disease, hemorrhoids, genitourinary system diseases, aplastic anemia (AA), pure red cell aplasia (PRCA), congenital dyserythropoietic anemia (CDA), myelodysplastic syndrome and various hematopoietic system tumor diseases, bone marrow necrosis, myelofibrosis, myelosclerosis, marble disease, bone marrow metastasis of extramedullary tumor diseases, infectious or non-infectious osteomyelitis, hyperlymphocytic function, renal insufficiency, hypopituitarism or hypothyroidism, liver disease, folic acid or vitamin B12 deficiency or utilization disorder, hemolytic anemia (HA), etc.

(1) Anemia caused by damage to bone marrow stromal cells

Bone marrow necrosis, myelofibrosis, myelosclerosis, marble disease, bone marrow metastasis of various extramedullary tumor diseases, and various infectious or non-infectious osteomyelitis can all affect blood cell production and lead to anemia due to damage to bone marrow stromal cells and the hematopoietic microenvironment (which can also damage hematopoietic cells).

(2) Anemia caused by hyperfunction of lymphocytes

T cell hyperfunction can lead to hematopoietic failure through direct killing of cytotoxic T cells (perforin) or (and) T cell factor-mediated hematopoietic cell apoptosis. Hyperfunction of B cells can produce anti-bone marrow cell autoantibodies, which in turn destroy or inhibit hematopoietic cells and lead to hematopoietic failure (immune-related pancytopenia).

(3) Anemia caused by abnormal levels of hematopoietic regulatory factors

Renal insufficiency, hypopituitarism or hypothyroidism, liver disease, etc. can all lead to anemia due to insufficient EPO production. Tumor diseases or certain viral infections can induce the body to produce more negative hematopoietic regulatory factors such as TNF, IFN, and inflammatory factors, which can also inhibit hematopoiesis and lead to anemia.

Anemia caused by hyperapoptosis of hematopoietic cells