Detailed process of luteal ovulation in vitro fertilization

With the development of society, IVF technology is also developing rapidly. The main process of IVF is ovulation induction and egg retrieval. For women who cannot conceive naturally, IVF can satisfy their wish to become parents. Many women who want to do IVF do not understand the detailed process of luteal ovulation induction. What is the detailed process of luteal ovulation induction? Let’s take a look at it next.

1. Controlled ovulation induction:

Because the length of the natural menstrual cycle varies from person to person, and there are also differences between different cycles of the same patient, it is not easy to arrange the time for egg retrieval. In addition, only one dominant follicle develops in the natural cycle, and only one embryo can be formed after fertilization. The pregnancy rate of transplanting one embryo is very low. Therefore, controlled superovulation is needed to enhance and improve ovarian function, so as to achieve the goal of not being restricted by the natural cycle, obtaining multiple healthy eggs, providing multiple embryo transplants, and synchronizing corpus luteum development with endometrial function as much as possible. The drug dosage is adjusted according to the patient's response to the drug. The number of eggs obtained will vary depending on the patient's age and drug dosage.

2. Monitoring follicles:

In order to evaluate the effect of ovarian stimulation and determine the time for egg retrieval, the ultrasound imaging system monitors the size of the follicles, and blood tests are used to check the E2 value (estrogen) and adjust the dosage of the medication. When two to three or more follicles are larger than 1.8 cm in diameter, and the number of follicles larger than 1.4 cm is equivalent to the E2 value, human chorionic gonadotropin (hCG) can be injected to promote follicle maturation. Egg retrieval is done 34-36 hours after hCG injection.

3. Egg retrieval:

The most commonly used method of egg retrieval is to insert the egg retrieval needle through the vaginal vault and directly reach the ovary to absorb the eggs under local anesthesia and under the guidance of an ultrasound imaging system. The eggs are then immediately transferred to a culture dish containing embryo culture medium under a microscope and cultured in a 37°C incubator.