Why does blastocyst transfer fail?

In recent years, there are more and more infertile people, and there are many reasons for infertility. However, the emergence of test-tube babies has given many people hope, and this technology has allowed many families to successfully have their own children. However, test-tube babies are not omnipotent, and failures may occur. Many people do not know why the test-tube babies fail. So why does the blastocyst transfer fail?

Failure of ovulation induction

Ovulation induction refers to the use of drugs to encourage women to release more eggs at one time. It is a key part of the prerequisite preparation for in vitro fertilization. If there is a problem with ovulation, it will seriously affect the subsequent process. As women age, their ovarian reserve will deteriorate, the number of follicles will decrease, and the quality will decline. Age is an important factor in the success of ovulation induction. For some women with premature ovarian failure, their success rate will be relatively low due to their low innate reserves.

In addition, women with polycystic ovary syndrome are prone to ovarian overstimulation during the ovulation induction process, which may cause physical discomfort. For healthy women, if the timing of ovulation induction is not chosen well, such as when they are sick, overly nervous, or overly tired, it can easily lead to ovulation induction failure.

Failed egg retrieval

Egg retrieval failure means that after a woman has ovulation induction, she has a certain number of follicles, but the oocytes in the follicles are not successfully extracted, but this probability is only one in a thousand.

It is worth noting that empty follicle syndrome can lead to egg retrieval failure. Experts in the nest explained that the so-called empty follicle syndrome refers to the absence of eggs in the follicles. The incidence rate is about 0.5%, and the cause is still unknown. However, a failed egg retrieval does not mean a complete failure. Some patients fail in the first egg retrieval, but can successfully retrieve the eggs after a delay of a few hours. Therefore, if the egg retrieval fails for the first time, please keep calm and do not worry too much.

Failure to fertilize an egg

After the egg is retrieved, it must combine with sperm to form a fertilized egg. This link is related to the quality of eggs and sperm, which is difficult to predict in advance, and the probability of an accident is about 3%. Experts in the nest remind that before doing in vitro fertilization, we cannot ignore the inspection of sperm quality.

Failure of embryo formation

The fertilized egg develops into an embryo, and qualified embryos will be transplanted into the mother's body. If the quality of the fertilized egg is poor, it will affect the formation of the embryo, and there is a certain risk of failure.

Embryonic malformation

Here comes the point: the failure rate of the previous few links combined is less than 10%, and under normal circumstances the occurrence rate is less than about 5%. The biggest reason for the failure of in vitro fertilization is that the embryo does not develop well in the mother's body. When the mother does not have a good development environment, even if the seeds are of good quality, they cannot obtain nutrients from the soil and cannot take root and sprout. Therefore, for expectant mothers who are trying to have a child, while objectively understanding the technology of in vitro fertilization, they must always be kind to their bodies.

The growth of the fetus requires a good maternal environment, just like crops rely on fertile soil to grow. We cannot ignore our own physical factors, and we must always use various methods to enhance the fertility of the mother's body, the most important soil. This will not only increase the success rate of in vitro fertilization, but may also change the outcome of natural conception.