What to do with uterine fibroids? Gonadotropin treatment

Uterine fibroids are a common gynecological disease, but they can also cause adverse effects on women's reproductive health, life and work. They can be treated with medications, such as gonadotropin, or they can be treated with surgery depending on the condition.

Drug treatment

(1) Gonadotropin

GnRH-a agonists (GnRH-a) Currently, the commonly used GnRH-a in clinical practice include leuprorelin (Enanton), goserelin (Zoleide), triptorelin (Dapiga), etc. GnRH-a should not be used continuously for a long time. It is only used for pretreatment before surgery, generally for 3 to 6 months, to avoid causing severe menopausal symptoms caused by low estrogen. A small dose of estrogen can also be supplemented at the same time to counteract this side effect.

(2) Mifepristone is a progesterone antagonist that has been clinically tried in recent years to treat uterine fibroids. It can reduce the size of fibroids, but the fibroids often grow again after discontinuation of the drug.

(3) Danazol

Used for preoperative medication or treatment of uterine fibroids that are not suitable for surgery. Uterine fibroids may grow larger after medication is stopped. Danazol can cause liver damage and androgen-induced side effects (weight gain, acne, hoarse voice, etc.).

Surgery

Surgical treatment of uterine fibroids includes myomectomy and hysterectomy, which can be performed abdominally or vaginally, or endoscopically (hysteroscopy or laparoscopy). The choice of surgical procedure and approach depends on factors such as the patient's age, whether or not they have fertility requirements, the size and location of the fibroids, and medical technology conditions.

(1) Myomectomy

Surgery to remove uterine fibroids while preserving the uterus is mainly used for young women under 40 who wish to retain their fertility. It is suitable for patients with larger fibroids, heavy menstruation, compression symptoms, infertility due to fibroids, submucosal fibroids, and fast-growing fibroids without malignant transformation.

(2) Hysterectomy

For patients with obvious symptoms, those with the possibility of malignant transformation of fibroids, and those with no desire to have children, hysterectomy is recommended. Hysterectomy can be performed with total hysterectomy or subtotal hysterectomy. For older women, total hysterectomy is more appropriate. The possibility of cervical malignancy must be excluded before surgery.

Diet

You should eat more whole grains such as corn and beans. You can also regularly eat some nutritious dried fruits such as peanuts, sesame seeds, melon seeds, etc. In addition, eat and drink on time and in regular amounts to avoid overeating.

The patient's meals should be light, and it is best not to eat irritating foods such as mutton, dog meat, shrimp, crab, eel, salted fish, and black fish.

You can eat more seaweed foods, such as nori, kelp, sea cabbage, wakame, etc. Seaweed contains the most minerals such as calcium, iron, sodium, magnesium, phosphorus, iodine, etc. Modern science believes that eating seaweed foods regularly can effectively regulate the acidity and alkalinity of the blood and avoid excessive consumption of alkaline elements (calcium and zinc) in the body due to acid neutralization.