Causes of vulvar fibroid disease

There are many common diseases. When treating diseases, we should choose multiple treatment methods, which will be very helpful for disease control. Common diseases are colds and coughs. These diseases are easy to occur. After suffering from them, medication is a good choice and is very helpful for controlling the disease. Many people are not familiar with vulvar fibroma. What are the causes of vulvar fibroma? The following is a detailed introduction.

Causes of vulvar fibroid disease:

1. Causes of disease

Vulvar fibroma generally originates from the fibrous tissue deep in the perineum or round ligament and is formed by the proliferation of fibroblasts.

2. Pathogenesis

Microscopically, vulvar fibroma shows parallel fibrous cords that are wavy or coiled together. The substance is composed of mature fibroblasts and collagen fibers that are woven in bundles. The cell nucleus is spindle-shaped, with myxoid degeneration in some places and no mitotic figures. The capsule is fibrous connective tissue with irregularly lobed, smooth and hard surface. The cross section is dense gray-white fibrous tissue, arranged in bundles, crisscrossing or in a whorl shape. The stroma is generally denser and contains more collagen fibers, that is, the cross-section of the fibroid is a dense, hard, grayish-white fibrous structure.

Diagnostic tests

Vulvar fibromas mostly occur in the labia majora, and rarely occur in the labia minora, clitoris, and round ligament. It grows slowly and is generally asymptomatic. Occasionally, due to friction, ulcers may form on the surface, and symptoms of falling and pain may occur. Examination shows that the labia majora are mung bean to cherry size, 0.6 to 8 cm in diameter, smooth, hard, pedunculated growths with grooves on the surface, and the color is like normal skin or light yellow, and they are usually single. Some can grow very large, with foreign literature reporting some weighing up to 268 pounds. They are spherical or oval in shape. When local blood circulation is impaired, the tumor may become cystic and soft in texture. If the tumor is too large, it may be accompanied by urination disorders and difficulty in sexual intercourse.

The diagnosis of vulvar fibroids is generally not difficult. The diagnosis can be confirmed based on clinical manifestations and laboratory tests. If the tumor develops rapidly and there is ulceration on the surface, a biopsy should be performed to confirm the diagnosis.

The following tests may be done to rule out other disorders:

1. Routine examination of vaginal discharge:

Observe the color and consistency of your vaginal discharge. Vaginal discharge is the fluid secreted by the female reproductive system, also known as leucorrhea. Examination may occasionally reveal leukocytosis.

2. Tumor marker examination: Tumor markers are chemical substances that reflect the presence of tumors.

(1) Classification

1) Produced by tumor tissue, including: differentiation antigens; embryonic antigens (AFP, CEA); isoenzymes (NSE); hormones (HCG); tissue-specific antigens (PSA, free PSA): mucins, glycoproteins, glycolipids (CA125); oncogenes and their products; polyamines, etc.

2) Produced after the interaction between tumor and host, including: serum ferritin; immune complexes; acute phase proteins; isoenzymes; interleukin receptors; tumor necrosis factor, etc.

3. Histopathological examination:

Microscopically, vulvar fibroma shows parallel fibrous cords that are wavy or coiled together. The substance is composed of mature fibroblasts and collagen fibers that are woven in bundles.

The cell nucleus is spindle-shaped, with myxoid degeneration in some places and no mitotic figures. The capsule is fibrous connective tissue with irregularly lobed, smooth and hard surface. The stroma is generally denser and contains more collagen fibers, that is, the cross-section of the fibroid is a dense, hard, grayish-white fibrous structure.

After understanding the cause of vulvar fibroma, the treatment of vulvar fibroma needs to be carried out according to the patient's cause. However, when treating vulvar fibroma, patients must also pay attention to not eating casually. Patients cannot choose cold or spicy foods, otherwise it will hinder the treatment of vulvar fibroma.