Congenital ovarian dysgenesis syndrome is a relatively common disease. It must be treated as early as possible to avoid the deterioration of the disease. In severe cases, it can cause infertility in female patients. So what are the symptoms of congenital ovarian dysgenesis syndrome? In the treatment of this disease, relevant preventive measures must be taken to avoid the deterioration of the disease. Let us learn more about it in detail. The clinical manifestations are short stature, underdeveloped genitals and secondary sexual characteristics, and a group of body developmental abnormalities. Height is generally less than 150 cm. The female vulva is immature, with a vagina and a small or absent uterus. The physical characteristics include multiple moles, ptosis, large and low ears, high palate, low posterior hairline, short and wide neck, webbed neck, barrel or shield-shaped chest, large distance between nipples, underdeveloped breasts and nipples, cubitus valgus, short 4th or 5th metacarpals or metatarsal bones, pass-through hands, lower limb lymphedema, renal malformation, and aortic arch stenosis. The levels of intellectual development vary. Life expectancy is the same as that of normal people. Maternal age does not appear to be associated with this developmental abnormality. LH and FSH increase significantly from the age of 10 to 11 years old, and the increase in FSH is greater than that in LH. The bone density of Turner patients is significantly lower than that of normal women of the same age. Except for 45,X, the chromosomes of Turner syndrome may have various mosaics, such as 45,X/46,XX, 45,X/47,XXX. Or 45, X/46, XX/47, XXX, etc. Clinical manifestations vary depending on which cell line predominates in the chimera. If normal sex chromosomes are in the majority, there will be fewer abnormal signs; conversely, if abnormal chromosomes are in the majority, there will be more typical abnormal signs. Turner syndrome can also be caused by abnormalities in the structure of sex chromosomes, such as X chromosome long arm isoarm Xi (Xq), short arm isoarm Xi (Xp), long arm or short arm deletion XXq-, XXp-, forming a circular Xxr or translocation. The clinical manifestations are related to the amount of deficiency. Those who lack it may still have residual follicles and may have menstruation, but will enter menopause after a few years. We hope that the above analysis of the clinical symptoms of congenital ovarian dysgenesis syndrome will help patients. We also hope that patients will build up confidence in treating the disease. Active treatment in the early stages of the disease can increase the chance of cure. We wish patients with congenital ovarian dysgenesis syndrome a speedy recovery. |
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