1. Physiological factors Long-term vegetarianism or malnutrition leads to insufficient protein intake in the body. For example, some people diet excessively, which results in a loss of muscle mass and a corresponding decrease in creatinine production. In pregnant women, the glomerular filtration rate increases, creatinine excretion increases, and this may also lead to a decrease in blood creatinine. 2. Disease factors People with muscle diseases such as myasthenia gravis and muscular dystrophy have reduced muscle metabolism and decreased creatinine production. Some liver diseases, such as cirrhosis, affect the body's metabolic function and may lead to low creatinine levels. 3. Drug effects Certain drugs may affect the metabolism and excretion of creatinine. For example, the use of drugs that promote renal excretion increases creatinine excretion. 4. Detection Error Errors in the laboratory testing process, such as problems with sample collection, storage, or testing methods. The testing equipment and standards may vary between different medical institutions. 5. Other situations After massive infusion of fluids, the blood is diluted and a temporary decrease in creatinine may occur. Hyperthyroidism and accelerated body metabolism may also lead to a decrease in creatinine values. In short, decreased creatinine may be caused by a variety of reasons. If you find that your creatinine is decreased, especially when accompanied by other uncomfortable symptoms, you should seek medical attention in time for further examination and diagnosis to determine the specific cause. |
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