This life-saving medicine, born in blood, saves tens of millions of people every year!

• Warfarin exerts its anticoagulant effect by inhibiting the synthesis of coagulation factors II, VII, IX, and X by vitamin K in liver cells. The effect is maintained for a long time after onset and is mainly used to prevent and treat thromboembolic diseases. For example, it can treat thromboembolic phlebitis, reduce the incidence and mortality of pulmonary embolism, and reduce the incidence of venous thrombosis in major surgical operations, rheumatic heart disease, hip fixation, heart valve replacement surgery, etc.

• The pharmacokinetic parameters of warfarin are relatively stable and better than other oral anticoagulants. For example, its efficacy is significantly better than aspirin in preventing stroke in patients with non-rheumatic atrial fibrillation. However, when treating or preventing thrombosis or embolism in pregnant patients, subcutaneous or intravenous heparin is more suitable.

• Although warfarin is effective, the dosage must be strictly controlled. Excessive use can easily cause bleeding. Bleeding can occur in any part of the body, especially the urinary system and digestive tract. In the early stages, there may also be ecchymosis, purpura, bleeding gums, and wounds that do not heal for a long time. Women may experience symptoms of excessive menstruation.