Diethylstilbestrol is a synthetic non-steroidal estrogen substance, but unlike steroidal substances, diethylstilbestrol is insoluble in water. It is a general term for a group of estrus hormone substances produced by stilbene compounds. It is also widely used in clinical medicine, and both men and women can take this therapeutic drug. Diethylstilbestrol is a synthetic nonsteroidal estrogen Diethylstilbestrol was first used as an oral contraceptive and received widespread popularity as soon as it was introduced. To date, this therapeutic drug has been widely used in clinical medicine. It is mainly used to treat multi-effect bleeding and amenorrhea caused by estrogen deficiency and hormone imbalance. It can also be used before induction of labor to increase the sensitivity of the uterine myometrium to oxytocin. The most common adverse effect of long-term use of diethylstilbestrol is the side effects of diethylstilbestrol, such as nausea, vomiting, dizziness and headache, etc., but this type of side effect is relatively easy to treat, but the effects of long-term use of diethylstilbestrol are far more than that. The following three major harms are also often produced: ❶Female hormone disorder Whether male or female, the body contains estrogen and androgen, and these two hormones tend to be in a state of balance. For patients with low estrogen, taking diethylstilbestrol to supplement estrogen is to balance the patient's body's hormones. However, if diethylstilbestrol is taken for a long time, it is easy to cause excessive estrogen in the patient's body, leading to female hormone disorder. Long-term use of ethinyl estradiol can easily cause a disorder in the body's hormone levels ❶ Women’s uterine wall is too thick For women with thin endometrium, taking diethylstilbestrol can increase the thickness of the endometrium, but if diethylstilbestrol is taken for a long time, it is easy to cause the thickness of the endometrium of women to continue to increase, thereby causing the uterine wall to be too thick. In this case, it can affect the implantation of the embryo combined with sperm and egg, and increase the difficulty of pregnancy for women. Long-term use of ethinyl estradiol by women can easily lead to thickening of the uterine wall ❶Male infertility After all, ethinyl stilbestrol belongs to the category of estrogen drugs. If men take it for too long, it is easy to cause virilization, and the secondary sexual characteristics will also disappear and shrink, thus affecting the formation of sperm. Over time, it is easy to cause male infertility, which is a very serious situation. Men who take ethinyl estradiol for a long time are very likely to become infertile. Not only can ethinyl estradiol not be taken for a long time, but it is also not suitable for excessive intake. Excessive intake will not only fail to treat the patient's own symptoms, but may even cause the harm mentioned in the report. Therefore, regarding the usage and dosage of ethinyl estradiol, patients are advised to consult a doctor before taking it. |
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